Robbiani Davide, MD, PhD

Publications -> 21180

• Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
  Weisblum, Y. Schmidt, F. Zhang, F. DaSilva, J. Poston, D. Lorenzi, J. C. Muecksch, F. Rutkowska, M. Hoffmann, H. H. Michailidis, E. Gaebler, C. Agudelo, M. Cho, A. Wang, Z. Gazumyan, A. Cipolla, M. Luchsinger, L. Hillyer, C. D. Caskey, M. Robbiani, D. F. Rice, C. M. Nussenzweig, M. C. Hatziioannou, T. Bieniasz, P. D.
  in Elife (2020) Vol.9 pp
  
• Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses
  Schmidt, F. Weisblum, Y. Muecksch, F. Michailidis, E. Lorenzi, J. C. C. Mendoza, P. Rutkowska, M. Bednarski, E. Gaebler, C. Agudelo, M. Cho, A. Wang, Z. Gazumyan, A. Cipolla, M. Caskey, M. Robbiani, D. F. Nussenzweig, M. C. Rice, C. M. Hatziioannou, T. Bieniasz, P. D.
  in J Exp Med (2020) Vol.217 pp
  
• Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
  Barnes, C. O. West, A. P., Jr. Huey-Tubman, K. E. Sharaf, N. G. Hoffman, P. R. Koranda, N. Gristick, H. B. Gaebler, C. Muecksch, F. Lorenzi, J. C. C. Finkin, S. Hagglof, T. Hurley, A. Millard, K. G. Weisblum, Y. Schmidt, F. Hatziioannou, T. Bieniasz, P. D. Caskey, M. Robbiani, D. F. Nussenzweig, M. C. Bjorkman, P. J.
  in Cell (2020) Vol. pp
  
• Convergent antibody responses to SARS-CoV-2 in convalescent individuals
  Robbiani, D. F. Gaebler, C. Muecksch, F. Lorenzi, J. C. C. Wang, Z. Cho, A. Agudelo, M. Barnes, C. O. Gazumyan, A. Finkin, S. Hagglof, T. Oliveira, T. Y. Viant, C. Hurley, A. Hoffmann, H. H. Millard, K. G. Kost, R. G. Cipolla, M. Gordon, K. Bianchini, F. Chen, S. T. Ramos, V. Patel, R. Dizon, J. Shimeliovich, I. Mendoza, P. Hartweger, H. Nogueira, L. Pack, M. Horowitz, J. Schmidt, F. Weisblum, Y. Michailidis, E. Ashbrook, A. W. Waltari, E. Pak, J. E. Huey-Tubman, K. E. Koranda, N. Hoffman, P. R. West, A. P., Jr. Rice, C. M. Hatziioannou, T. Bjorkman, P. J. Bieniasz, P. D. Caskey, M. Nussenzweig, M. C.
  in Nature (2020) Vol. pp
  
• A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations
  Wang, Q. Michailidis, E. Yu, Y. Hurley, A. M. Oren, D. A. Mayer, C. T. Gazumyan, A. Liu, Z. Zhou, Y. Schoofs, T. Yao, K. H. Nieke, J. P. Wu, J. Jiang, Q. Zou, C. Kabbani, M. Quirk, C. Oliveira, T. Chhosphel, K. Zhang, Q. Schneider, W. M. Jahan, C. Ying, T. Horowitz, J.Caskey, M. Jankovic, M. Robbiani, D. F. Wen, Y. de Jong, Y. P.
  in Cell Host Microbe (2020) Vol. pp
  
• Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
  Esswein, S. R. Gristick, H. B. Jurado, A. Keeffe, J. R. Lee, Y. E. Voll, A. V. Saeed, M. Nussenzweig, M. C. Rice, C. M. Robbiani, D. F. MacDonald, M. R. Bjorkman, P. J.
  in Proc Natl Acad Sci U S A (2020) Vol.117 pp9865-9875
  
• A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques
  Van Rompay, K. K. A. Coffey, L. L. Kapoor, T. Keesler, R. I. Jurado, A. Peace, A. Agudelo, M. Watanabe, J. Usachenko, J. Singapuri, A. Immareddy, R. Ardeshir, A. Stuart, J. B. Bournazos, S. Ravetch, J. V. Balderes, P. J. Lorenz, I. C. Esswein, S. R. Keeffe, J. R. Bjorkman, P. J. Wang, Q. Rice, C. M. MacDonald, M. R. Nussenzweig, M. C.Robbiani, D. F.
  in Proc Natl Acad Sci U S A (2020) Vol.117 pp7981-7989
  
• Risk of Zika microcephaly correlates with features of maternal antibodies
  Robbiani, D. F. Olsen, P. C. Costa, F. Oliveira, T. Y. Nery, N., Jr. Aromolaran, A. do Rosario, M. S. Sacramento, G. A. Cruz, J. S. Khouri, R. Wunder, E. A., Jr. Mattos, A. de Paula Freitas, B. Sarno, M. Archanjo, G. Daltro, D. Carvalho, G. B. S. Pimentel, K. de Siqueira, I. C. de Almeida, J. R. M. Henriques, D. F. Lima, J. A. Vasconcelos, P. F. C. Schaefer-Babajew, D.Azzopardi, S. A. Bozzacco, L. Gazumyan, A. Belfort, R., Jr. Alcantara, A. P.
  in J Exp Med (2019) Vol.216 pp2302-2315
  
• A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
  Keeffe, J. R. Van Rompay, K. K. A. Olsen, P. C. Gazumyan, A. Azzopardi, S. A. Schaefer-Babajew, D. Lee, Y. E. Stuart, J. B. Singapuri, A. Watanabe, J. Usachenko, J. Ardeshir, A. Saeed, M. Agudelo, M. Eisenreich, T. Bournazos, S. Oliveira, T. Y. Rice, C. M. Coffey, L. L. MacDonald, M. R. Bjorkman, P. J. Nussenzweig, M. C. Robbiani, D. F.
  in Cell Rep (2018) Vol.25 pp1385-1394 e7
  
• Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico
  Robbiani, D. F. Bozzacco, L. Keeffe, J. R. Olsen, P. C. Gazumyan, A. Schaefer-Babajew, D. Avila-Rios, S. Nogueira, L. Patel, R. Azzopardi, S. A. Uhl, L. F. K. Saeed, M. Sevilla-Reyes, E. E. Agudelo, M. Yao, K. H. Golijanin, J. Gristick, H. B. Lee, Y. E. Hurley, A. Caskey, M. Pai, J. Oliveira, T. Wunder, E. A., Jr. Sacramento, G.Nery, N., Jr. Orge, C. Costa, F. Reis, M. G. Thomas, N. M.
  in Cell (2017) Vol.169 pp597-609 e11
  
• RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaks
  Rommel, P. C. Oliveira, T. Y. Nussenzweig, M. C.
  in J Exp Med (2017) Vol.214 pp815-831
  
• The cell cycle restricts activation-induced cytidine deaminase activity to early G1
  Wang, Q. Kieffer-Kwon, K. R. Oliveira, T. Y. Yao, K. Pai, J. Cao, Z. Dose, M. Casellas, R. Jankovic, M. Nussenzweig, M. C. Robbiani, D. F.
  in J Exp Med (2016) Vol.214 pp49-58
  
• Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity
  Casellas, R. Basu, U. Yewdell, W. T. Robbiani, D. F. Di Noia, J. M.
  in Nat Rev Immunol (2016) Vol.16 pp164-76
  
• A New Way to Diversify Antibodies by DNA Transposition
  Robbiani, D. F. Nussenzweig, M. C.
  in Cell (2016) Vol.164 pp601-2
  
• Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching
  Dong, J. Panchakshari, R. A. Zhang, T. Hu, J. Volpi, S. A. Meyers, R. M. Ho, Y. J. Du, Z. Robbiani, D. F. Meng, F. Gostissa, M. Nussenzweig, M. C. Manis, J. P. Alt, F. W.
  in Nature (2015) Vol.525 pp134-139
  
• Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma
  Robbiani, D. F. Deroubaix, S. Feldhahn, N. Callen, E. Wang, Q. Jankovic, M. Silva, I. T. Rommel, P. C. Bosque, D. Eisenreich, T. Nussenzweig, A. Nussenzweig, M. C.
  in Cell (2015) Vol.162 pp727-37
  
• B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity
  Qian, J. Wang, Q. Dose, M. Kieffer-Kwon, K. R. Resch, W. Liang, G. Tang, Z. Mathe, E. Benner, C. Dubois, W. Nelson, S. Vian, L. Oliveira, T. Y. Jankovic, M. Hakim, O. Gazumyan, A. Pavri, R. Awasthi, P. Song, B. Liu, G. Chen, L. Zhu, S. Feigenbaum, L. Staudt, L.Murre, C. Ruan, Y. Robbiani, D. F. Pan-Hammarstrom, Q. Nussenzweig, M. C.
  in Cell (2014) Vol.159 pp1524-37
  
• miR-217 is an oncogene that enhances the germinal center reaction
  de Yebenes, V. G. Bartolome-Izquierdo, N. Nogales-Cadenas, R. Mur, S. M. Martinez, N. Di Lisio, L. Robbiani, D. F. Pascual-Montano, A. Canamero, M. Piris, M. A. Ramiro, A. R.
  in Blood (2014) Vol.124 pp229-39
  
• Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during montuse developme
  Rommel, P. C. Bosque, D. Gitlin, A. D. Heintz, N. Casellas, R. Nussenzweig, M. C. Kriaucionis, S. Robbiani, D. F.
  in PLoS One (2013) Vol.8 ppe69208
  
• Identification of early replicating fragile sites that contribute to genome instability
  Barlow, J. H. Faryabi, R. B. Callen, E. Malhowski, A. Chen, H. T. Gutierrez-Cruz, G. Sun, H. W. McKinnon, P. Wright, G. Casellas, R. Robbiani, D. F. Staudt, L. Fernandez-Capetillo, O. Nussenzweig, A.
  in Cell (2013) Vol.152 pp620-32
  
• Role of 53BP1 oligomerization in regulating double-strand break repair
  Lottersberger, F. Bothmer, A. Robbiani, D. F. de Lange, T.
  in Proc Natl Acad Sci U S A (2013) Vol.110 pp2146-51
  
• Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching
  Di Virgilio, M. Callen, E. Yamane, A. Jankovic, M. Gitlin, A. D. Feldhahn, N. Resch, W. Oliveira, T. Y. Chait, B. T. Nussenzweig, A. Casellas, R. Robbiani, D. F. Nussenzweig, M. C.
  in Science (2013) Vol.339 pp711-5
  
• 53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma
  Jankovic, M. Feldhahn, N. Oliveira, T. Y. Kieffer-Kwon, K. R. Yamane, A. Resch, W. Klein, I. Robbiani, D. F. Casellas, R. Nussenzweig, M. C.
  in Mol Cell (2013) Vol.49 pp623-31
  
• RPA accumulation during class switch recombination represents 5′-3′ DNA-end resection during the S-G2/M phase of the cell cycle
  Yamane, A. Robbiani, D. F. Resch, W. Nakahashi, H. Oliveira, T. Rommel, P. C. Brown, E. J. Nussenzweig, A. Nussenzweig, M. C. Casellas, R.
  in Cell Rep (2013) Vol.3 pp138-47
  
• Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching
  Bothmer, A. Rommel, P. C. Gazumyan, A. Reczek, C. R. Muellenbeck, M. F. Schaetzlein, S. Edelmann, W. Chen, P. L. Brosh, R. M., Jr. Casellas, R. Ludwig, T. Baer, R. Nussenzweig, A. Nussenzweig, M. C. Robbiani, D. F.
  in J Exp Med (2012) Vol.210 pp115-23
  
• RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1
  Munoz, M. C. Laulier, C. Gunn, A. Robbiani, D. F. Nussenzweig, A. Stark, J. M.
  in J Biol Chem (2012) Vol.287 pp40618-28
  
• Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase
  Robbiani, D. F. Nussenzweig, M. C.
  in Annu Rev Pathol (2012) Vol.8 pp79-103
  
• The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo
  Feldhahn, N. Ferretti, E. Robbiani, D. F. Deroubaix, S. Selleri, L. Nussenzweig, A. Nussenzweig, M. C.
  in EMBO J (2012) Vol.31 pp4045-56
  
• DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes
  Hakim, O. Resch, W. Yamane, A. Kieffer-Kwon, K. R. Jankovic, M. Oliveira, T. Bothmer, A. Voss, T. C. Ansarah-Sobrinho, C. Mathe, E. Liang, G. Cobell, J. Nakahashi, H. Robbiani, D. F. Nussenzweig, A. Hager, G. L. Nussenzweig, M. C. Casellas, R.
  in Nature (2012) Vol.484 pp69-74
  
• Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes
  Klein, I. A. Resch, W. Jankovic, M. Yamane, A. Nakahashi, H. Di Virgilio, M. Bothmer, A. Nussenzweig, A. Robbiani, D. F. Casellas, R. Nussenzweig, M. C.
  in Cell (2011) Vol.147 pp95-106
  
• Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1
  Bothmer, A. Robbiani, D. F. Di Virgilio, M. Klein, I. A. Feldhahn, N. Barlow, J. Chen, H. T. Bosque, D. Callen, E. Nussenzweig, A. Nussenzweig, M. C.
  in Mol Cell (2011) Vol.42 pp319-29
  
• Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
  Yamane, A. Resch, W. Kuo, N. Li, Z. Sun, H. W. Robbiani, D. F. McBride, K. Nussenzweig, M. C. Casellas, R.
  in Nat Immunol (2010) Vol.12 pp62-9
  
• 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
  Bothmer, A. Robbiani, D. F. Feldhahn, N. Nussenzweig, A. Nussenzweig, M. C.
  in J Exp Med (2010) Vol.207 pp855-65
  
• Role of the translocation partner in protection against AID-dependent chromosomal translocations
  Jankovic, M. Robbiani, D. F. Dorsett, Y. Xu, Y. Tarakhovsky, A. Nussenzweig, A. Nussenzweig, M. C.
  in Proc Natl Acad Sci U S A (2009) Vol.107 pp187-92
  
• AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
  Robbiani, D. F. Bunting, S. Feldhahn, N. Camps, J. Deroubaix, S. McBride, K. M. Klein, I. A. Stone, G. Eisenreich, T. R. Ried, T. Nussenzweig, A. Nussenzweig, M. C.
  in Mol Cell (2009) Vol.36 pp631-41
  
• AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
  Robbiani, D. F. Bothmer, A. Callen, E. Dorsett, Y. Difilippantonio, S. Bolland, D. J. Chen, H. T. Corcoran, A. E. Nussenzweig, A. Nussenzweig, M. C.
  in Cell (2008) Vol.135 pp1028-38
  
• MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation
  Dorsett, Y. McBride, K. M. Jankovic, M. Thai, T. H. Robbiani, D. F. Di Virgilio, M. Reina San-Martin, B. Heidkamp, G. Schwickert, T. A. Eisenreich, T. Rajewsky, K. Nussenzweig, M. C.
  in Immunity (2008) Vol.28 pp630-8
  
• AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies
  Chesi, M. Robbiani, D. F. Sebag, M. Affer, M. Tiedemann, R. Valdez, R. Palmer, S. E. Haas, S. S. Stewart, A. K. Fonseca, R. Kremer, R. Cattoretti, G. Bergsagel, P. L.
  in Cancer Cell (2008) Vol.13 pp167-80
  
• A role for AID in chromosome translocations between c-myc and the IgH variable region
  Dorsett, Y. Robbiani, D. F. Jankovic, M. Eisenreich, T. R. Nussenzweig, M. C.
  in J Exp Med (2007) Vol.204 pp2225-32
  
• Osteopontin dysregulation and lytic bone lesions in multiple myeloma
  Robbiani, D. F. Colon, K. Ely, S. Chesi, M. Bergsagel, P. L.
  in Hematol Oncol (2006) Vol.25 pp16-20
  
• Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation
  McBride, K. M. Gazumyan, A. Woo, E. M. Robbiani, D. F. Chait, B. T. Nussenzweig, M. C.
  in Proc Natl Acad Sci U S A (2006) Vol.103 pp8798-803
  
• Maintained rules of development in a mouse B-cell tumor
  Robbiani, D. F. Colon, K. Affer, M. Bergsagel, P. L.
  in Leukemia (2005) Vol.19 pp1278-80
  
• Bone lesions in molecular subtypes of multiple myeloma
  Robbiani, D. F. Chesi, M. Bergsagel, P. L.
  in N Engl J Med (2004) Vol.351 pp197-8
  
• Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma
  Trudel, S. Ely, S. Farooqi, Y. Robbiani, D. F. Chesi, M. Bergsagel, P. L.
  in Blood (2004) Vol.103 pp3521-8
  
• Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells
  Beaulieu, S. Robbiani, D. F. Du, X. Ignatius, R. Wei, Y. Ponath, P. Young, J. W. Pope, M. Steinman, R. M. Mojsov, S.
  in J Immunol (2002) Vol.169 pp2925-36
  
• Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma
  Chesi, M. Brents, L. A. Ely, S. A. Robbiani, D. F. Mesri, E. A. Kuehl, W. M. Bergsagel, P. L.
  in Blood (2001) Vol.97 pp729-36
  
• The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes
  Robbiani, D. F. Finch, R. A. Jager, D. Sartorelli, A. C. Randolph, G. J.
  in Cell (2000) Vol.103 pp757-68
  
• Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
  Randolph, G. J. Inaba, K. Robbiani, D. F. Muller, W. A.
  in Immunity (2000) Vol.11 pp753-61
  
• Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis
  Uguccioni, M. Gionchetti, P. Robbiani, D. F. Peruzzo, S. Campieri, M. Baggiolini, M.
  in Am J Pathol (1999) Vol.155 pp331-6