Lanzavecchia Antonio, MD

Publications -> 20816

• AncesTree: An interactive immunoglobulin lineage tree visualizer
  Foglierini, M. Pappas, L. Lanzavecchia, A. Corti, D. Perez, L.
  in PLoS Comput Biol (2020) Vol.16 ppe1007731
  
• Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin
  Cassotta, A. Paparoditis, P. Geiger, R. Mettu, R. R. Landry, S. J. Donati, A. Benevento, M. Foglierini, M. Lewis, D. J. M. Lanzavecchia, A. Sallusto, F.
  in J Exp Med (2020) Vol.217 pp
  
• Dynamics in protein translation sustaining T cell preparedness
  Wolf, T. Jin, W. Zoppi, G. Vogel, I. A. Akhmedov, M. Bleck, C. K. E. Beltraminelli, T. Rieckmann, J. C. Ramirez, N. J. Benevento, M. Notarbartolo, S. Bumann, D. Meissner, F. Grimbacher, B. Mann, M. Lanzavecchia, A. Sallusto, F. Kwee, I. Geiger, R.
  in Nat Immunol (2020) Vol.8 pp927-937
  
• Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
  Pinto, D. Park, Y. J. Beltramello, M. Walls, A. C. Tortorici, M. A. Bianchi, S. Jaconi, S. Culap, K. Zatta, F. De Marco, A. Peter, A. Guarino, B. Spreafico, R. Cameroni, E. Case, J. B. Chen, R. E. Havenar-Daughton, C. Snell, G. Telenti, A. Virgin, H. W. Lanzavecchia, A. Diamond, M. S. Fink, K. Veesler, D. Corti, D.
  in Nature (2020) Vol. pp
  
• Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles
  Petrova, V. N. Sawatsky, B. Han, A. X. Walz, L. Parker, E. Pieper, K. Anderson, C. A. de Vries, R. D. Lanzavecchia, A. Kellam, P. von Messling, V. de Swart, R. L. Russell, C. A.
  in Sci Immunol (2019) Vol.4 pppii: eaay6125
  
• Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
  Pinto, D. Fenwick, C. Caillat, C. Guseva, S. Dehez, F. Chipot, C. Barbieri, S. Minola, A. Jarrossay, D. Tomaras, G. D. Shen, X. Riva, A. Tarkowski, M. Schwartz, O. Bruel, T. Dufloo, J. Seaman, M. S. Montefiori, D. C. Lanzavecchia, A. Corti, D. Pantaleo, G. Weissenhorn, W.
  in Cell Host Microbe (2019) Vol.26 pp623-637
  
• The challenges of primary biliary cholangitis: What is new and what needs to be done
  Terziroli Beretta-Piccoli, B. Mieli-Vergani, G. Vergani, D. Adams, D. Alpini, G. Banales, J. M. Beuers, U. Bjornsson, E. Bowlus, C. Carbone, M. Chazouilleres, O. Dalekos, G. De Gottardi, A. Harada, K. Hirschfield, G. Invernizzi, P. Jones, D. Krawitt, E. Lanzavecchia, A. Lian, Z. X. Ma, X. Manns, M. Mavilio, D. Quigley, E. M. Sallusto, F. Shimoda, S. Strazzabosco, M. Swain, M. Tanaka, A.
  in J Autoimmun (2019) Vol.105 pp102328
  
• A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients
  Cassotta, A. Mikol, V. Bertrand, T. Le Parc, J. Ferrari, P. Dumas, J. Auer, M. Deisenhammer, F. Gastaldi, M. Franciotta, D. Silacci-Fregni, C. Fernandez Rodriguez, B. Giacchetto-Sasselli, I. Foglierini, M. Jarrossay, D. Geiger, R. Sallusto, F. Lanzavecchia, A. Piccoli, L.
  in Nat Med (2019) Vol.25 pp1402-1407
  
• Identification of a Novel Non-desmoglein Autoantigen in Pemphigus Vulgaris
  Di Lullo, G. Calabresi, V. Mariotti, F. Lanzavecchia, A. Di Zenzo, G.
  in Front Immunol (2019) Vol.10 pp1391
  
• Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
  Marcandalli, J. Fiala, B. Ols, S. de van der Schueren, W. Snijder, J. Hodge, E. Benhaim, M. Ravichandran, R. Carter, L. Sheffler, W. Brunner, L. Lawrenz, M. Dubois, P. Lanzavecchia, A. Sallusto, F. Lee, K. K. Veesler, D. Correnti, C. E. Stewart, L. J. Baker, D. Lore, K. Perez, L. King, N. P.
  in Cell (2019) Vol.176 pp1420-1431 e17
  * J. Marcandalli and B. Fiala contributed equally to this work. L. Perez and N. P. King contributed equally to this work and are co-corresponding authors.
• Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
  Lee, J. Paparoditis, P. Horton, A. P. McDaniel, J. R. Jung, J. Boutz, D. R. Hussein, D. A. Tanno, Y. Pappas, L. Ippolito, G. C. Corti, D. Lanzavecchia, A. Georgiou, G.
  in Cell Host Microbe (2019) Vol.13 pp367-376
  
• Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
  Walls, A. C. Xiong, X. Park, Y. J. Snijder, J. Quispe, J. Cameroni, E. Gopal, R. Dai, M. Lanzavecchia, A. Zambon, M. Rey, F. A. Corti, D. Veesler, D.
  in Cell (2019) Vol.176 pp1026-1039
  
• The Antibody Response to Plasmodium falciparum: Cues for Vaccine Design and the Discovery of Receptor-Based Antibodies
  Tan, J. Piccoli, L. Lanzavecchia, A.
  in Annu Rev Immunol (2018) Vol.37 pp225-246
  
• Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4
  Stewart-Jones, G. B. E. Chuang, G. Y. Xu, K. Acharya, P. Tsybovsky, Y. Ou, L. Zhang, B. Fernandez-Rodriguez, B. Gilardi, V. Silacci-Fregni, C. Beltramello, M. Baxa, U. Druz, A. Kong, W. P. Thomas, P. V. Yang, Y. Foulds, K. E. Todd, J. P. Wei, H. Salazar, A. M. Scorpio, D. G. Carragher, B. Potter, C. S. Corti, D. Mascola, J. R. Lanzavecchia, A. Kwong, P. D.
  in Proc Natl Acad Sci U S A (2018) Vol.115 pp12265-12270.
  
• T cells in patients with narcolepsy target self-antigens of hypocretin neurons
  Latorre, D. Kallweit, U. Armentani, E. Mele, F. Cassotta, A. Jovic, S. Jarrossay, D. Mathis, J. Zellini, F. Becher, B. Lanzavecchia, A. Khatami, R. Manconi, M. Tafti, M. Bassetti, C. L. Sallusto, F.
  in Nature (2018) Vol.562 pp63-68
  
• Influenza hemagglutinin membrane anchor
  Benton, D. J. Nans, A. Calder, L. J. Neu, U. Lin, Y. P. Ketelaars, E. Kallewaard, N. L. Corti, D. Lanzavecchia, A. Gamblin, S. J. Rosenthal, P. B. Skehel, J. J.
  in Proc Natl Acad Sci U S A (2018) Vol.115 pp10112-10117
  
• An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells
  Aschenbrenner, D. Foglierini, M. Jarrossay, D. Weiner, H. L. Kuchroo, V. K. Lanzavecchia, A. Notarbartolo, S. Sallusto, F.
  in Nat Immunol (2018) Vol.19 pp1126-1136
  
• An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor
  Martinez-Martin, N. Marcandalli, J. Huang, C. S. Perotti, M. Foglierini, M. Ho, H. Dosey, A. M. Shriver, S. Payandeh, J. Leitner, A. Lanzavecchia, A. Perez, L. Ciferri, C.
  in Cell (2018) Vol.174 pp1158-1171
  * L. Perez and C. Ciferri contributed equally; N M-M, LP and CC are co-corresponding authors
• Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone
  Pickett, J. E. Thompson, J. M. Sadowska, A. Sellman, B. R. Minola, A. Corti, D. Lanzavecchia, A. Miller, L. S. Thorek, D. L.
  in Bone Res (2018) Vol.6 pp13
  
• A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
  Tan, J. Sack, B. K. Oyen, D. Piccoli, L. Barbieri, S. Foglierini, M. Fregni, C. S. Marcandalli, J. Jongo, S. Abdulla, S. Perez, L. Corradin, G. Varani, L. Sallusto, F. Sim, B. K. L. Hoffman, S. L. Kappe, S. H. I. Daubenberger, C. Wilson, I. A. Lanzavecchia, A.
  in Nat Med (2018) Vol.24 pp401-407
  * Tan J., Sack B. K., Oyen D., Zenklusen I., Piccoli L. contributed equally to this work.
• Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection
  Lloyd, K. A. Steen, J. Amara, K. Israelsson, L. Lundstrom, S. L. Zhou, D. Zubarev, R. A. Reed, E. Piccoli, L. Gabay, C. Lanzavecchia, A. Baeten, D. Lundberg, K. Mueller, D. L. Klareskog, L. Malmstrom, V. Gronwall, C.
  in Eur J Immunol (2018) Vol.48 pp1030-1045
  
• Pillars Article: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994. 179:1109-1118
  Sallusto, F. Lanzavecchia, A.
  in J Immunol (2018) Vol.200 pp887-896
  
• Dissecting human antibody responses: useful, basic and surprising findings
  Lanzavecchia, A.
  in EMBO Mol Med (2018) Vol. ppe8879
  
• Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae
  Pennini, M. E. De Marco, A. Pelletier, M. Cvitkovic, R. Beltramello, M. Cameroni, E. Bianchi, S. Zatta, F. Zhao, W. Xiao, X. Camara, M. M. DiGiandomenico, A. Semenova, E. Lanzavecchia, A. Warrener, P. Suzich, J. Wang, Q. Corti, D. Stover, C. K.
  in Nat Commun (2017) Vol.8 pp1991
  
• Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
  Haks, M. C. Bottazzi, B. Cecchinato, V. Del Giudice, G. Kaufmann, S. H. E. Lanzavecchia, A. Lewis, D. J. M. Maertzdorf, J. Mantovani, A. Sallusto, F. Sironi, M. Uguccioni, M. Ottenhoff, T. H. M.
  in Front Immunol (2017) Vol.8 pp1563
  
• Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with protection from vertical transmission
  Mele, F. Fornara, C. Jarrossay, D. Arossa, A. Spinillo, A. Lanzavecchia, A. Gerna, G. Sallusto, F. Lilleri, D.
  in PLoS One (2017) Vol.12 ppe0187731
  
• Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus
  Sastry, M. Zhang, B. Chen, M. Kong, W. P. Chuang, G. Y. Ko, K. Kumar, A. Silacci, C. Thom, M. Salazar, A. M. Corti, D. Lanzavecchia, A. Taylor, G. Mascola, J. R. Graham, B. S. Kwong, P. D.
  in PLoS One (2017) Vol.12 ppe0186854
  
• A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
  Wang, J. Bardelli, M. Espinosa, D. A. Ng, T. S. Bianchi, S. Simonelli, L. Lim, E. X. Y. Foglierini, M. Zatta, F. Jaconi, S. Beltramello, M. Cameroni, E. Fibriansah, G. Shi, J. Barca, T. Pagani, I. Rubio, A. Broccoli, V. Vicenzi, E. Graham, V. Pullan, S. Dowall, S. Hewson, R. Jurt, S.Zerbe, O. Stettler, K. Lanzavecchia, A. Sallusto, F. Cavalli, A.
  in Cell (2017) Vol.171 pp229-241 e15
  * J. Wang and M. Bardelli contributed equally ; S-M Lok, L.Varani and D. Corti contributed equally.
• Role of B cells in T helper cell responses in a mouse model of asthma
  Wypych, T. P. Marzi, R. Wu, G. F. Sallusto, F.
  in J Allergy Clin Immunol (2017) Vol.141 pp1395-1410
  
• Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
  Pieper, K. Tan, J. Piccoli, L. Barbieri, S. Chen, Y. Silacci-Fregni, C. Wolf, T. Jarrossay, D. Anderle, M. Abdi, A. Ndungu, F. M. Doumbo, O. K. Traore, B. Tran, T. M. Jongo, S. Zenklusen, I. Crompton, P. D. Daubenberger, C. Bull, P. C. Sallusto, F. Lanzavecchia, A.
  in Nature (2017) Vol.548 pp597-601
  * Pieper K., Tan J., Piccoli, L. contributed equally to this work.
• Tackling influenza with broadly neutralizing antibodies
  Corti, D. Cameroni, E. Guarino, B. Zhu, Q. Lanzavecchia, A.
  in Curr Opin Virol (2017) Vol.24 pp60-69
  
• Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor
  Chan, S. Frasch, A. Mandava, C. S. Quintana, M. D. P. Vesterlund, M. Ghorbal, M. Joannin, N. Franzen, O. Lopez-Rubio, J. J. Barbieri, S. Lanzavecchia, A. Sanyal, S. Wahlgren, M.
  in Nat Microbiol (2017) Vol.2 pp17068
  
• Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? T-Cell Heterogeneity, Plasticity, and Selection in Humans
  Sallusto, F. Cassotta, A. Hoces, D. Lanzavecchia, A.
  in Cold Spring Harb Perspect Biol (2017) Vol.10 ppa029421
  
• High-avidity IgA protects the intestine by enchaining growing bacteria
  Moor, K. Diard, M. Sellin, M. E. Wotzka, S. Y. Toska, A. Bakkeren, E. Arnoldini, M. Bansept, F. Co, A. D. Voller, T. Minola, A. Fernandez-Rodriguez, B. Agatic, G. Barbieri, S. Piccoli, L. Casiraghi, C. Corti, D. Lanzavecchia, A. Regoes, R. R. Loverdo, C. Stocker, R. Brumley, D. R. Hardt, W. D. Slack, E.
  in Nature (2017) Vol.544 pp498-502
  
• Protection of calves by a prefusion-stabilized bovine RSV F vaccine
  Zhang, B. Chen, L. Silacci Fregni, C. Boyington, J. C. Druz, A. Joyce, M. G. Guzman, E. Kong, W. P. Lai, Y. T. Stewart-Jones, G. B. E. Tsybovsky, Y. Yang, Y. Zhou, T. Baxa, U. Mascola, J. R. Corti, D. Lanzavecchia, A. Taylor, G. Kwong, P. D.
  in npj Vaccines (2017) Vol.2 pp7
  
• Social network architecture of human immune cells unveiled by quantitative proteomics
  Rieckmann, J. C. Geiger, R. Hornburg, D. Kveler, K. Jarrossay, D. Sallusto, F. Shen-Orr, S. S. Lanzavecchia, A. Mann, M. Meissner, F.
  in Nat Immunol (2017) Vol.18 pp583-593
  
• L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
  Geiger, R. Rieckmann, J. C. Wolf, T. Feng, Y. Fuhrer, T. Kogadeeva, M. Picotti, P. Meissner, F. Mann, M. Zamboni, N. Sallusto, F. Lanzavecchia, A.
  in Cell (2016) Vol.167 pp829-842 e13
  Geiger R. and Lanzavecchia A are co-corresponding authors.
• Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes
  Kallewaard, N. L. Corti, D. Collins, P. J. McAuliffe, J. M. Benjamin, E. Wachter-Rosati, L. Palmer-Hill, F. J. Yuan, A. Q. Walker, P. A. Vorlaender, M. K. Bianchi, S. Guarino, B. De Marco, A. Vanzetta, F. Agatic, G. Foglierini, M. Pinna, D. Fernandez-Rodriguez, B. Fruehwirth, A. Silacci, C. Ogrodowicz, R. W. Martin, S. R. Sallusto, F. Suzich, J. A. Lanzavecchia, A. Zhu, Q. Gamblin, S. J. Skehel, J. J.
  in Cell (2016) Vol.166 pp596-608
  
• Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection
  Stettler, K. Beltramello, M. Espinosa, D. A. Cassotta, A. Bianchi, S. Vanzetta, F. Minola, A. Jaconi, S. Mele, F. Foglierini, M. Pedotti, M. Simonelli, L. Dowall, S. Atkinson, B. Percivalle, E. Simmons, C. P. Varani, L. Blum, J. Baldanti, F. Cameroni, E. Hewson, R. Harris, E. Lanzavecchia, A. Sallusto, F. Corti, D.
  in Science (2016) Vol.353 pp823-6
  K. S and M. B contributed equally to this work; D. A. E. ; V. G. ; A. C. ; S. B. and F. V contributed equally to this work; F. S. and D. C contributed equally to this work and are co-corresponding authors.
• Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
  Ellebrecht, C. T. Bhoj, V. G. Nace, A. Mao, X. Cho, M. J. Di Zenzo, G. Lanzavecchia, A. Seykora, J. T. Cotsarelis, G. Milone, M. C. Payne, A. S.
  in Science (2016) Vol.353 pp179-84
  
• Antibody-guided vaccine design: identification of protective epitopes
  Lanzavecchia, A. Fruhwirth, A. Perez, L.
  in Curr Opin Immunol (2016) Vol.41 pp62-67
  
• Platelet-derived growth factor-alpha receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer
  Kabanova, A. Marcandalli, J. Zhou, T. Baxa, U. Tsybovsky, Y. Lilleri, D. Silacci-Fregni, C. Foglierini, M. Fernandez-Rodriguez, B. M. Druz, A. Zhang, B. Geiger, R. Pagani, M. Sallusto, F. Kwong, P. D. Corti, D. Lanzavecchia, A. Perez, L.
  in Nat Microbiol (2016) Vol.1 pp16082
  Anna Kabanova, Jessica Marcandalli, Tongqing Zhou equally contributed to this work; Antonio Lanzavecchia1and Laurent Perez jointly supervised this work.
• Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1beta production by myeloid cells
  Ronchi, F. Basso, C. Preite, S. Baumjohann, D. Perlini, L. Lanzavecchia, A. Sallusto, F.
  in Nat Commun (2016) Vol.7 pp11541
  Francesca Ronchi and Camilla Basso equally contributed to this work.
• Monoclonal antibodies to different components of the human cytomegalovirus (HCMV) pentamer gH/gL/pUL128L and trimer gH/gL/gO as well as antibodies elicited during primary HCMV infection prevent epithelial cell syncytium formation
  Gerna, G. Percivalle, E. Perez, L. Lilleri, D.
  in J Virol (2016) Vol.90 pp6216-23
  
• Rapid generation of a human monoclonal antibody to combat Middle East respiratory syndrome
  Corti, D. Passini, N. Lanzavecchia, A.
  in J Infect Public Health (2016) Vol.9 pp231-5
  
• Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis
  De Benedictis, P. Minola, A. Rota Nodari, E. Zecchin, B. Salomoni, A. Foglierini, M. Agatic, G. Vanzetta, F. Lavenir, R. Lepelletier, A. Bentley, E. Weiss, R. Cattoli, G. Capua, I. Sallusto, F. Wright, E. Lanzavecchia, A. Bourhy, H. Corti, D.
  in EMBO Mol Med (2016) Vol.8 pp407-21
  Paola De Benedictis and Andrea Minola equally contributed to this work.
• SARS-like WIV1-CoV poised for human emergence
  Menachery, V. D. Yount, B. L., Jr. Sims, A. C. Agnihothram, S. S. Gralinski, L. E. Graham, R. L. Scobey, T. Plante, J. A. Royal, S. R. Swanstrom, J. Sheahan, T. P. Pickles, R. J. Corti, D. Randell, S. H. Lanzavecchia, A. Marasco, W. A. Baric, R. S.
  in Proc Natl Acad Sci U S A (2016) Vol.113 pp3048-53
  
• Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
  Corti, D. Misasi, J. Mulangu, S. Kanekiyo, M. Wollen, S. Ploquin, A. Doria-Rose, N. A. Staupe, R. P. Bailey, M. Shi, W. Choe, M. Marcus, H. Thompson, E. A. Cagigi, A. Silacci, C. Fernandez-Rodriguez, B. Perez, L. Sallusto, F. Vanzetta, F. Agatic, G. Cameroni, E. Kisalu, N. Gordon, I. Ledgerwood, J. E. Mascola, J. R. Graham, B. S. Muyembe-Tamfun, J. J. Trefry, J. C. Lanzavecchia, A.
  in Science (2016) Vol.351 pp1339-42
  Davide Corti and John Misasi equally contributed to this work; John C. Trefry, Antonio Lanzavecchia, and Nancy J. Sullivan equally contributed to this work.
• Structural and molecular basis for Ebola virus neutralization by protective human antibodies
  Misasi, J. Gilman, M. S. Kanekiyo, M. Cagigi, A. Mulangu, S. Corti, D. Ledgerwood, J. E. Lanzavecchia, A. Cunningham, J. Muyembe-Tamfun, J. J. Baxa, U. Graham, B. S. Xiang, Y. Sullivan, N. J. McLellan, J. S.
  in Science (2016) Vol.351 pp1343-6
  John Misasi, Morgan S. A. Gilman, Masaru Kanekiyo, Miao Gui, equally contributed to this work; Ye Xiang, Nancy J. Sullivan, Jason S. McLellan equally contributed to this work.
• A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens
  Tan, J. Pieper, K. Piccoli, L. Foglierini, M. Geiger, R. Tully, C. M. Jarrossay, D. Ndungu, F. M. Wambua, J. Bejon, P. Fregni, C. S. Fernandez-Rodriguez, B. Barbieri, S. Bianchi, S. Marsh, K. Thathy, V. Corti, D. Sallusto, F. Bull, P. Lanzavecchia, A.
  in Nature (2016) Vol.529 pp105-9
  Joshua Tan, Kathrin Pieper, Luca Piccoli equally contributed to this work and Peter Bull and Antonio Lanzavecchia jointly supervised this work.
• A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
  Menachery, V. D. Yount, B. L., Jr. Debbink, K. Gralinski, L. E. Plante, J. A. Graham, R. L. Scobey, T. Ge, X. Y. Donaldson, E. F. Randell, S. H. Lanzavecchia, A. Marasco, W. A. Shi, Z. L. Baric, R. S.
  in Nat Med (2015) Vol.21 pp1508-13
  Vineet D Menachery and Ralph Baric are co-corresponding authors.
• Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells
  Preite, S. Baumjohann, D. Foglierini, M. Ronchi, F. Rodriguez, B. M. Corti, D. Lanzavecchia, A. Sallusto, F.
  in Eur J Immunol (2015) Vol.45 pp3010-21
  
• Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
  Corti, D. Zhao, J. Pedotti, M. Agnihothram, S. Fett, C. Fernandez-Rodriguez, B. Foglierini, M. Agatic, G. Vanzetta, F. Gopal, R. Langrish, C. J. Barrett, N. A. Sallusto, F. Baric, R. S. Varani, L. Zambon, M. Perlman, S. Lanzavecchia, A.
  in Proc Natl Acad Sci U S A (2015) Vol.112 pp10473-8
  D.C. and J.Z. contributed equally to this work.
• Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody
  Xiong, X. Corti, D. Liu, J. Foglierini, M. Calder, L. J. Martin, S. R. Lin, Y. P. Walker, P. A. Collins, P. J. Monne, I. Suguitan, A. L., Jr. Santos, C. Temperton, N. J. Subbarao, K. Lanzavecchia, A. Gamblin, S. J. Skehel, J. J.
  in Proc Natl Acad Sci U S A (2015) Vol.112 pp9430-5
  X.X., D.C., and J.L. contributed equally to this work.
• Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
  Lindesmith, L. C. Beltramello, M. Swanstrom, J. Corti, D. Lanzavecchia, A. Baric, R. S.
  in Open Forum Infect Dis (2015) Vol.2 ppofv084
  
• Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis
  Piccoli, L. Campo, I. Fregni, C. S. Minola, A. Sallusto, F. Luisetti, M. Corti, D. Lanzavecchia, A.
  in Nat Commun (2015) Vol.6 pp7375
  
• ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
  Mele, F. Basso, C. Leoni, C. Becattini, S. Latorre, D. Lanzavecchia, A. Sallusto, F. Monticelli, S.
  in Nat Commun (2015) Vol.6 pp6431
  Federica Sallusto and Silvia Monticelli equally contributed to this work and are co-corresponding authors.
• Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge
  Sholukh, A. M. Watkins, J. D. Vyas, H. K. Lakhashe, S. K. Thorat, S. Zhou, M. Hemashettar, G. Bachler, B. C. Forthal, D. N. Villinger, F. Sattentau, Q. J. Weiss, R. A. Agatic, G. Corti, D. Lanzavecchia, A. Heeney, J. L. Ruprecht, R. M.
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• Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies
  Kabanova, A. Perez, L. Lilleri, D. Agatic, G. Becattini, S. Preite, S. Fuschillo, D. Percivalle, E. Sallusto, F. Gerna, G. Corti, D. Lanzavecchia, A.
  in Proc Natl Acad Sci U S A (2014) Vol.111 pp17965-70
  A.K. and L.P. contributed equally to this work.
• Rapid development of broadly influenza neutralizing antibodies through redundant mutations
  Pappas, L. Foglierini, M. Piccoli, L. Turrini, F. Silacci, C. Fernandez-Rodriguez, B. Agatic, G. Giacchetto-Sasselli, I. Pellicciotta, G. Sallusto, F. Zhu, Q. Vicenzi, E. Corti, D. Lanzavecchia, A.
  in Nature (2014) Vol.516 pp418-22
  Davide Corti and Antonio Lanzavecchia equally contributed to this work.
• Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells
  Corti, D. Lanzavecchia, A.
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• Particle Conformation Regulates Antibody Access to a Conserved GII.4 Norovirus Blockade Epitope
  Lindesmith, L. C. Donaldson, E. F. Beltramello, M. Corti, D. Swanstrom, J. Debbink, K. Jones, T. A. Lanzavecchia, A. Baric, R. S.
  in J Virol (2014) Vol.88 pp8826-42
  
• Within-Host Evolution Results in Antigenically Distinct GII.4 Noroviruses
  Debbink, K. Lindesmith, L. C. Ferris, M. T. Beltramello, M. Corti, D. Lanzavecchia, A. Baric, R. S.
  in J Virol (2014) Vol.88 pp7244-7255
  
• The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells
  Gupta, S. Gach, J. S. Becerra, J. C. Pudney, J. Moldoveanu, Z. Joseph, S. B. Landucci, G. Supnet, M. J. Ping, L. H. Corti, D. Moldt, B. Hel, Z. Lanzavecchia, A. Ruprecht, R. M. Burton, D. R. Mestecky, J. Anderson, D. J. Forthal, D. N.
  in PLoS Pathog (2013) Vol.9 ppe1003776
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• Cross-neutralization of four paramyxoviruses by a human monoclonal antibody
  Corti, D. Bianchi, S. Vanzetta, F. Perez, L. Agatic, G. Guarino, B. Silacci, C. Marcandalli, J. Marsland, B. J. Piralla, A. Percivalle, E. Sallusto, F. Baldanti, F. Lanzavecchia, A.
  in Nature (2013) Vol.501 pp439-43
  
• Emergence of New Pandemic GII.4 Sydney Norovirus Strain Correlates With Escape From Herd Immunity
  Debbink, K. Lindesmith, L. C. Donaldson, E. F. Beltramello, M. Corti, D. Swanstrom, J. Lanzavecchia, A. Vinje, J. Baric, R. S.
  in J Infect Dis (2013) Vol.208 pp1877-87
  
• A functional BCR in human IgA and IgM plasma cells
  Pinto, D. Montani, E. Bolli, M. Sallusto, F. Lanzavecchia, A. Jarrossay, D.
  in Blood (2013) Vol.121 pp4110-4
  
• Fetal Human Cytomegalovirus Transmission Correlates with Delayed Maternal Antibodies to gH/gL/pUL128-130-131 Complex during Primary Infection
  Lilleri, D. Kabanova, A. Revello, M. G. Sarasini, A. Genini, E. Sallusto, F. Lanzavecchia, A. Corti, D. Gerna, G.
  in PLoS One (2013) Vol.8 ppe59863
  
• Broadly neutralizing antiviral antibodies
  Corti, D. Lanzavecchia, A.
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• Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype
  Baumjohann, D. Preite, S. Reboldi, A. Ansel, K. M. Lanzavecchia, A. Sallusto, F.
  in Immunity (2013) Vol.38 pp596-605
  Dirk Baumjohann and Federica Sallusto are co-corresponding authors.
• Therapeutic Efficacy of Antibodies Lacking FcgammaR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies
  Williams, K. L. Sukupolvi-Petty, S. Beltramello, M. Sallusto, F. Lanzavecchia, A. Diamond, M. S. Harris, E.
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  Formal Correction: There is an error in the article title, which is missing the word "binding". The title should instead read: "Therapeutic Efficacy of Antibodies Lacking Fcγ Receptor Binding against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies"
• Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking
  Simonelli, L. Pedotti, M. Beltramello, M. Calzolai, L. Sallusto, F. Lanzavecchia, A. Varani, L.
  in PLoS One (2013) Vol.8 ppe55561
  Luca Simonelli, Mattia Pedotti contributed equally to this work.
• Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface
  Di Zenzo, G. Di Lullo, G. Corti, D. Sinistro, A. Vanzetta, F. Didona, B. Cianchini, G. Hertl, M. Eming, R. Amagai, M. Ohyama, B. Hashimoto, T. Sloostra, J. Sallusto, F. Zambruno, G. Lanzavecchia, A.
  in J Clin Invest (2012) Vol.122 pp3781-90
  Giovanni Di Zenzo, Giulia Di Lullo, and Davide Corti contributed equally to this work.
• Human Th17 subsets
  Sallusto, F. Zielinski, C. E. Lanzavecchia, A.
  in Eur J Immunol (2012) Vol.42 pp2215-20
  
• Antibodies against neutralization epitopes of human cytomegalovirus gH/gL/pUL128-130-131 complex and virus spreading may correlate with virus control in vivo
  Lilleri, D. Kabanova, A. Lanzavecchia, A.
  in J Clin Immunol (2012) Vol.32 pp1324-31
  
• T-cell trafficking in the central nervous system
  Sallusto, F. Impellizzieri, D. Basso, C. Uccelli, A. Lanzavecchia, A. Engelhardt, B.
  in Immunol Rev (2012) Vol.248 pp216-27
  
• Immunogenetic Mechanisms Driving Norovirus GII.4 Antigenic Variation
  Lindesmith, L. C. Beltramello, M. Donaldson, E. F. Swanstrom, J. Debbink, K. Lanzavecchia, A. Baric, R. S.
  in PLoS Pathog (2012) Vol.8 ppe1002705
  Lisa C. Lindesmith, Martina Beltramello contributed equally to this work.
• Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C
  Gomez, C. E. Perdiguero, B. Jimenez, V. Ghneim, K. Haddad, E. K. Quakkerlaar, E. D. Delaloye, J. Harari, A. Roger, T. Dunhen, T. Sekaly, R. P. Melief, C. J. Calandra, T. Sallusto, F. Lanzavecchia, A. Wagner, R. Pantaleo, G. Esteban, M.
  in PLoS One (2012) Vol.7 ppe35485
  
• Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta
  Zielinski, C. E. Mele, F. Aschenbrenner, D. Ronchi, F. Gattorno, M. Monticelli, S. Lanzavecchia, A. Sallusto, F.
  in Nature (2012) Vol.484 pp514-8
  
• Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells
  Duhen, T. Duhen, R. Lanzavecchia, A. Campbell, D. J.
  in Blood (2012) Vol.119 pp4430-40
  
• Ralph M. Steinman 1943-2011
  Lanzavecchia, A. Sallusto, F.
  in Cell (2012) Vol.147 pp1216-7
  
• Characterization of Neutralizing Profiles in HIV-1 Infected Patients from whom the HJ16, HGN194 and HK20 mAbs were Obtained
  Balla-Jhagjhoorsingh, S. S. Willems, B. Heyndrickx, L. Janssens, W. Seaman, M. S. Corti, D. Lanzavecchia, A. Davis, D. Vanham, G.
  in PLoS One (2011) Vol.6 ppe25488
  
• Memory in disguise
  Sallusto, F. Lanzavecchia, A.
  in Nat Med (2011) Vol.17 pp1182-3
  
• A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
  Corti, D. Voss, J. Gamblin, S. J. Macagno, A. Jarrossay, D. Vachieri, S. G. Pinna, D. Minola, A. Vanzetta, F. Silacci, C. Fernandez-Rodriguez, B. M. Agatic, G. Bianchi, S. Giacchetto-Sasselli, I. Calder, L. Sallusto, F. Collins, P. Haire, L. F. Temperton, N. Langedijk, J. P. Skehel, J. J. Lanzavecchia, A.
  in Science (2011) Vol.333 pp850-6
  Davide Corti, Jarrod Voss, Steven J. Gamblin, Giosiana Codoni contributed equally to this work. John J. Skehel and Antonio Lanzavecchia are co-corresponding authors.
• In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection
  de Alwis, R. Beltramello, M. Messer, W. B. Wahala, W. M. Kraus, A. Olivarez, N. P. Pham, Q. Brian, J. Tsai, W. Y. Wang, W. K. Halstead, S. Kliks, S. Diamond, M. S. Baric, R. Lanzavecchia, A. Sallusto, F. de Silva, A. M.
  in PLoS Negl Trop Dis (2011) Vol.5 ppe1188
  
• High throughput cellular screens to interrogate the human T and B cell repertoires
  Corti, D. Sallusto, F. Lanzavecchia, A.
  in Curr Opin Immunol (2011) Vol.23 pp430-5
  
• An Anti-HIV-1 V3 Loop Antibody Fully Protects Cross-Clade and Elicits T-Cell Immunity in Macaques Mucosally Challenged with an R5 Clade C SHIV
  Watkins, J. D. Siddappa, N. B. Lakhashe, S. K. Sholukh, A. Hemashettar, G. Wong, Y. L. Yoon, J. K. Wang, W. Novembre, F. J. Villinger, F. Ibegbu, C. Patel, K. Corti, D. Agatic, G. Vanzetta, F. Bianchi, S. Heeney, J. L. Sallusto, F. Lanzavecchia, A. Ruprecht, R. M.
  in PLoS One (2011) Vol.6 ppe18207
  Jennifer D. Watkins, Nagadenahalli B. Siddappa contributed equally to this work.
• Dissecting the human immunologic memory for pathogens
  Zielinski, C. E. Corti, D. Mele, F. Lanzavecchia, A. Sallusto, F.
  in Immunol Rev (2011) Vol.240 pp40-51
  
• Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors
  Quakkelaar, E. D. Redeker, A. Haddad, E. K. McCaughey, S. M. Duhen, T. Filali-Mouhim, A. Goulet, J. P. Loof, N. M. Ossendorp, F. Perdiguero, B. Heinen, P. Gomez, C. E. Kibler, K. V. Koelle, D. M. Sekaly, R. P. Sallusto, F. Lanzavecchia, A. Pantaleo, G. Esteban, M. Tartaglia, J. Jacobs, B. L. Melief, C. J.
  in PLoS One (2011) Vol.6 ppe16819
  
• Strain-Transcending Fc-Dependent Killing of Plasmodium falciparum by Merozoite Surface Protein 2 Allele-Specific Human Antibodies
  Stubbs, J. Olugbile, S. Saidou, B. Corradin, G. Lanzavecchia, A.
  in Infect Immun (2010) Vol.79 pp1143-52
  
• Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41
  Sabin, C. Corti, D. Buzon, V. Lutje Hulsik, D. Hinz, A. Vanzetta, F. Agatic, G. Silacci, C. Mainetti, L. Scarlatti, G. Sallusto, F. Weiss, R. Lanzavecchia, A. Weissenhorn, W.
  in PLoS Pathog (2010) Vol.6 ppe1001195
  Charles Sabin, Davide Corti, Victor Buzon equally contributed to this work.
• CD4(+) CD25(+) Treg regulate the contribution of CD8(+) T-cell subsets in repopulation of the lymphopenic environment
  Almeida, A. R. Ciernik, I. F. Sallusto, F.
  in Eur J Immunol (2010) Vol.40 pp3478-88
  
• Chondroitin Sulfate A-Adhering Plasmodium falciparum-Infected Erythrocytes Express Functionally Important Antibody Epitopes Shared by Multiple Variants
  Barfod, L. Dobrilovic, T. Magistrado, P. Viwami, F. Bruun, J. Dahlback, M. Bernasconi, N. L. Fried, M. John, D. Duffy, P. E. Salanti, A. Lanzavecchia, A. Lim, C. T. Ndam, N. T. Higgins, M. K. Hviid, L.
  in J Immunol (2010) Vol.185 pp7553-61
  
• From vaccines to memory and back
  Sallusto, F. Lanzavecchia, A. Araki, K.
  in Immunity (2010) Vol.33 pp451-63
  Federica Sallusto and Rafi Ahmed are co-corresponding authors.
• Monocytes join the dendritic cell family
  Sallusto, F. Lanzavecchia, A.
  in Cell (2010) Vol.143 pp339-40
  Federica Sallusto and Antonio Lanzavecchia are co-corresponding authors.
• The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity
  Beltramello, M. Williams, K. L. Simmons, C. P. Simonelli, L. Quyen, N. T. Sukupolvi-Petty, S. Navarro-Sanchez, E. Young, P. R. de Silva, A. M. Rey, F. A. Varani, L. Whitehead, S. S. Diamond, M. S. Harris, E. Lanzavecchia, A. Sallusto, F.
  in Cell Host Microbe (2010) Vol.8 pp271-83
  Antonio Lanzavecchia and Federica Sallusto are co-corresponding authors.
• Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness
  Pietzsch, J. Scheid, J. F. Mouquet, H. Seaman, M. S. Jankovic, M. Corti, D. Lanzavecchia, A. Nussenzweig, M. C.
  in J Exp Med (2010) Vol.207 pp1995-2002
  
• Current Opinion in Immunology. Vaccines. Introduction
  Ertl, H. C. Lanzavecchia, A.
  in Curr Opin Immunol (2010) Vol.22 pp355-7
  
• Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
  Corti, D. Suguitan, A. L., Jr. Pinna, D. Fernandez-Rodriguez, B. M. Vanzetta, F. Santos, C. Luke, C. J. Torres-Velez, F. J. Temperton, N. J. Weiss, R. A. Sallusto, F. Subbarao, K. Lanzavecchia, A.
  in J Clin Invest (2010) Vol.120 pp1663-73
  Davide Corti and Amorsolo L. Suguitan Jr. contributed equally to this work.
• CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function
  Rivino, L. Gruarin, P. Haringer, B. Lozza, L. Steckel, B. Weick, A. Sugliano, E. Jarrossay, D. Kuhl, A. A. Loddenkemper, C. Abrignani, S. Sallusto, F. Lanzavecchia, A. Geginat, J.
  in J Exp Med (2010) Vol.207 pp565-77
  P. Gruarin and B. Häringer contributed equally to this paper.
• Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus
  Rockx, B. Donaldson, E. Frieman, M. Corti, D. Lanzavecchia, A. Baric, R. S.
  in J Infect Dis (2010) Vol.201 pp946-55
  
• Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
  Corti, D. Langedijk, J. P. Hinz, A. Vanzetta, F. Fernandez-Rodriguez, B. M. Silacci, C. Pinna, D. Jarrossay, D. Balla-Jhagjhoorsingh, S. Willems, B. Zekveld, M. J. Dreja, H. O'Sullivan, E. Pade, C. Orkin, C. Jeffs, S. A. Montefiori, D. C. Davis, D. Weissenhorn, W. McKnight, A. Heeney, J. L. Sallusto, F. Sattentau, Q. J. Weiss, R. A. Lanzavecchia, A.
  in PLoS One (2010) Vol.5 ppe8805
  
• Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex
  Macagno, A. Bernasconi, N. L. Vanzetta, F. Sarasini, A. Revello, M. G. Gerna, G. Sallusto, F. Lanzavecchia, A.
  in J Virol (2009) Vol.84 pp1005-13
  
• Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity
  Sallusto, F. Lanzavecchia, A.
  in Eur J Immunol (2009) Vol.39 pp2076-82
  
• Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
  Duhen, T. Geiger, R . Jarrossay, D. Sallusto, F.
  in Nat Immunol (2009) Vol.10 pp857-63
  Thomas Duhen and Rebekka Geiger contributed equally to this work.
• Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells
  Geiger, R . Duhen, T. Lanzavecchia, A.
  in J Exp Med (2009) Vol.206 pp1525-34
  
• Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein
  Voss, D. Pfefferle, S. Drosten, C. Traggiai, E. Lanzavecchia, A. Becker, S.
  in Virol J (2009) Vol.6 pp79
  
• Human B cell memory
  Lanzavecchia, A. Sallusto, F.
  in Curr Opin Immunol (2009) Vol.21 pp298-304
  
• Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
  Soerli, J. Barfod, L. Lavstsen, T. Lanzavecchia, A. Hviid, L.
  in Parasite Immunol (2009) Vol.31 pp341-6
  
• Clonal dissection of the human memory B-cell repertoire following infection and vaccination
  Pinna, D. Corti, D. Jarrossay, D. Lanzavecchia, A.
  in Eur J Immunol (2009) Vol.39 pp1260-70
  
• Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells
  Napolitani, G. Acosta-Rodriguez, E. V. Lanzavecchia, A.
  in Eur J Immunol (2009) Vol.39 pp1301-12
  Giorgio Napolitani, Eva V. Acosta-Rodriguez contributed equally to this work.
• Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets
  Khurana, S. Suguitan, A. L., Jr. Rivera, Y. Lanzavecchia, A. Sallusto, F. Manischewitz, J. King, L. R. Subbarao, K. Golding, H.
  in PLoS Med (2009) Vol.6 ppe1000049
  
• Human Th17 cells in infection and autoimmunity
  Sallusto, F. Lanzavecchia, A.
  in Microbes Infect (2009) Vol.11 pp620-4
  
• C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
  Reboldi, A. Coisne, C. Baumjohann, D. Bottinelli, D. Lira, S. Uccelli, A. Lanzavecchia, A. Engelhardt, B. Sallusto, F.
  in Nat Immunol (2009) Vol.10 pp514-23
  
• Dendritic cell migration to peripheral lymph nodes
  Martin-Fontecha, A. Lanzavecchia, A. Sallusto, F.
  in Handb Exp Pharmacol (2008) Vol. pp31-49
  
• CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection
  Cocco, M. Bellan, C. Tussiwand, R. Traggiai, E. Lazzi, S. Mannucci, S. Bronz, L. Palummo, N. Ginanneschi, C. Tosi, P. Lanzavecchia, A. Manz, M. G. Leoncini, L.
  in Am J Pathol (2008) Vol.173 pp1369-78
  
• CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming
  Martin-Fontecha, A. Baumjohann, D. Guarda, G. Hons, M. Lanzavecchia, A. Sallusto, F.
  in J Exp Med (2008) Vol.205 pp2561-74
  *Alfonso Martín-Fontecha and Federica Sallusto are co-corresponding authors.
• Activated Lymph Nodes Recruit Blood Borne NK Cells and Effector T Cells:Implications for Adaptive T Cell Responses
  Martin-Fontecha, A. Guarda, G. Lanzavecchia, A.
  in Current Immunology Reviews (2008) Vol.4 pp20-27
  
• Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge
  Rockx, B. Corti, D. Donaldson, E. Stadler, K. Lanzavecchia, A. Baric, R.
  in J Virol (2008) Vol.82 pp3220-35
  B.R. and D.C. contributed equally to this work.
• The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells
  Lozza, L. Rivino, L. Guarda, G. Rinaldi, A. Bertoni, F. Sallusto, F. Lanzavecchia, A. Geginat, J.
  in Eur J Immunol (2007) Vol.38 pp30-9
  
• Human monoclonal antibodies by immortalization of memory B cells
  Lanzavecchia, A. Corti, D. Sallusto, F.
  in Curr Opin Biotechnol (2007) Vol.18 pp523-8
  
• Pillars article: Antigen-specific interaction between T and B cells. 1985
  Lanzavecchia, A.
  in J Immunol (2007) Vol.179 pp7206-8
  
• Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
  Acosta-Rodriguez, E. V. Napolitani, G. Lanzavecchia, A.
  in Nat Immunol (2007) Vol.8 pp942-9
  Federica Sallusto and Eva Acosta are co-corresponding authors.
• Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate
  Reiner, S. L. Sallusto, F. Lanzavecchia, A.
  in Science (2007) Vol.317 pp622-5
  Steven L. Reiner, Federica Sallusto, Antonio Lanzavecchia are corresponding authors.
• Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies
  Zhu, Z. Chakraborti, S. He, Y. Sheahan, T. Xiao, X. Hensley, L. E. Prabakaran, P. Rockx, B. Sidorov, I. A. Corti, D. Vogel, L. Feng, Y. Kim, J. O. Wang, L. F. Baric, R. Lanzavecchia, A. Curtis, K. M. Nabel, G. J. Subbarao, K. Jiang, S. Dimitrov, D. S.
  in Proc Natl Acad Sci U S A (2007) Vol.104 pp12123-8
  S.C., Y.H., A.R., T.S., and X.X. contributed equally to this work.
• Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza
  Simmons, C. P. Bernasconi, N. L. Suguitan, A. L. Ward, J. M. Chau, N. V. Hien, T. T. Sallusto, F. Ha do, Q. Farrar, J. de Jong, M. D. Lanzavecchia, A. Subbarao, K.
  in PLoS Med (2007) Vol.4 ppe178
  Cameron P. Simmons, Nadia L. Bernasconi, Amorsolo L. Suguitan Jr., Kimberly Mills contribuited equally to this work; Antonio Lanzavecchia and Kanta Subbarao are co-corresponding authors.
• L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells
  Guarda, G. Hons, M. Soriano, S. F. Polley, R. Martin-Fontecha, A. Stein, J. V. Germain, R. N. Lanzavecchia, A. Sallusto, F.
  in Nat Immunol (2007) Vol.8 pp743-52
  
• Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
  Acosta-Rodriguez, E. V. Rivino, L. Geginat, J. Gattorno, M. Lanzavecchia, A. Sallusto, F. Napolitani, G.
  in Nat Immunol (2007) Vol.8 pp639-46
  Federica Sallusto and Giorgio Napolitani are co-corresponding authors.
• Toll-like receptors and innate immunity in B-cell activation and antibody responses
  Lanzavecchia, A. Sallusto, F.
  in Curr Opin Immunol (2007) Vol.19 pp268-74
  
• Duration, combination and timing: the signal integration model of dendritic cell activation
  Macagno, A. Napolitani, G. Lanzavecchia, A.
  in Trends Immunol (2007) Vol.28 pp227-33
  
• Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
  Barfod, L. Bernasconi, N. L. Dahlback, M. Andersen, P. H. Salanti, A. Ofori, M. F. Turner, L. Resende, M. Nielsen, M. A. Theander, T. G. Sallusto, F. Lanzavecchia, A. Hviid, L.
  in Mol Microbiol (2006) Vol.63 pp335-47
  Lea Barfod and Nadia Bernasconi contributed equally to this work.
• Distinct expression pattern of IFN-alpha and TNF-alpha in juvenile idiopathic arthritis synovial tissue
  Gattorno, M. Chicha, L. Gregorio, A. Rossi, F. Jarrossay, D. Lanzavecchia, A. Martini, A. Manz, M. G.
  in Rheumatology (Oxford) (2006) Vol.46 pp657-65
  
• Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases
  Ghittoni, R. Napolitani, G. Benati, D. Patrussi, L. Laghi Pasini, F. Lanzavecchia, A. Baldari, C. T.
  in Eur J Immunol (2006) Vol.36 pp2885-93
  
• Understanding and making use of human memory B cells
  Lanzavecchia, A. Bernasconi, N. Traggiai, E. Corti, D. Sallusto, F.
  in Immunol Rev (2006) Vol.211 pp303-9
  
• A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression
  Macagno, A. Molteni, M. Rinaldi, A. Lanzavecchia, A. Rossetti, C. Sallusto, F.
  in J Exp Med (2006) Vol.203 pp1481-92
  Annalisa Macagno and Federica Sallusto are co-corresponding authors.
• Toll-like receptor stimulation as a third signal required for activation of human naive B cells
  Ruprecht, C. R. Lanzavecchia, A.
  in Eur J Immunol (2006) Vol.36 pp810-6
  
• Regulation of peripheral T cell activation by calreticulin
  Porcellini, S. Traggiai, E. Schenk, U. Matteoli, M. Lanzavecchia, A. Michalak, M. Grassi, F.
  in J Exp Med (2006) Vol.203 pp461-71
  
• Characterization of severe acute respiratory syndrome coronavirus membrane protein
  Voss, D. Kern, A. Traggiai, E. Stadler, K. Lanzavecchia, A. Becker, S.
  in FEBS Lett (2006) Vol.580 pp968-73
  
• Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development
  Onai, N. Obata-Onai, A. Tussiwand, R. Manz, M. G.
  in J Exp Med (2006) Vol.203 pp227-38
  N. Onai and A. Obata-Onai contributed equally to this work.
• ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells
  Wirths, S. Lanzavecchia, A.
  in Eur J Immunol (2005) Vol.35 pp3433-41
  
• Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
  Napolitani, G. Rinaldi, A. Bertoni, F. Lanzavecchia, A.
  in Nat Immunol (2005) Vol.6 pp769-76
  
• Human adaptive immune system Rag2-/-gamma(c)-/- mice
  Chicha, L. Tussiwand, R. Traggiai, E. Bronz, L. Piffaretti, J. C. Lanzavecchia, A. Manz, M. G.
  in Ann N Y Acad Sci (2005) Vol.1044 pp236-43
  
• Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
  Ruprecht, C. R. Gattorno, M. Ferlito, F. Martini, A. Lanzavecchia, A. Sallusto, F.
  in J Exp Med (2005) Vol.201 pp1793-803
  
• Understanding the generation and function of memory T cell subsets
  Lanzavecchia, A. Sallusto, F.
  in Curr Opin Immunol (2005) Vol.17 pp326-32
  
• T cell costimulation by chemokine receptors
  Molon, B. Gri, G. Bettella, M. Lanzavecchia, A. Martinez, A. C. Manes, S. Viola, A.
  in Nat Immunol (2005) Vol.6 pp465-71
  Santos Manes and Antonella Viola are co-corresponding authors.
• Immune subversion by Helicobacter pylori
  Baldari, C. T. Lanzavecchia, A. Telford, J. L.
  in Trends Immunol (2005) Vol.26 pp199-207
  
• Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses
  Yang, Z. Y. Werner, H. C. Kong, W. P. Traggiai, E. Lanzavecchia, A. Nabel, G. J.
  in Proc Natl Acad Sci U S A (2005) Vol.102 pp797-801
  
• Lead and follow: the dance of the dendritic cell and T cell
  Lanzavecchia, A. Sallusto, F.
  in Nat Immunol (2004) Vol.5 pp1201-2
  
• Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming
  Martin-Fontecha, A. Thomsen, L. L. Brett, S. Lipp, M. Lanzavecchia, A. Sallusto, F.
  in Nat Immunol (2004) Vol.5 pp1260-5
  Alfonso Martin-Fontecha and Federica Sallusto are co-corresponding authors.
• Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells
  Rivino, L. Messi, M. Jarrossay, D. Sallusto, F. Geginat, J.
  in J Exp Med (2004) Vol.200 pp725-35
  L. Rivino, M. Messi, and D. Jarrossay contributed equally to this work.
• Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice
  Feau, S. Facchinetti, V. Granucci, F. Jarrossay, D. Seresini, S. Protti, M. P. Lanzavecchia, A. Ricciardi-Castagnoli, P.
  in Blood (2004) Vol.105 pp697-702
  
• An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
  Traggiai, E. Becker, S. Subbarao, K. Uematsu, Y. Gismondo, M. R. Murphy, B. R. Rappuoli, R. Lanzavecchia, A.
  in Nat Med (2004) Vol.10 pp871-5
  
• Development of a human adaptive immune system in cord blood cell-transplanted mice
  Traggiai, E. Chicha, L. Mazzucchelli, L. Piffaretti, J. C. Lanzavecchia, A. Manz, M. G.
  in Science (2004) Vol.304 pp104-7
  Elisabetta Traggiai and Laurie Chicha contributed equally to this work.
• Central memory and effector memory T cell subsets: function, generation, and maintenance
  Sallusto, F. Geginat, J. Lanzavecchia, A.
  in Annu Rev Immunol (2004) Vol.22 pp745-63
  
• Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation
  Napolitani, G. Bortoletto, N. Racioppi, L. D'Oro, U.
  in Eur J Immunol (2003) Vol.33 pp2832-41
  
• Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
  MartIn-Fontecha, A. Sebastiani, S. Hopken, U. E. Lipp, M. Lanzavecchia, A. Sallusto, F.
  in J Exp Med (2003) Vol.198 pp615-21
  
• Cytokine-driven proliferation and differentiation of human naive, central memory and effector memory CD4+ T cells
  Geginat, J. Sallusto, F. Lanzavecchia, A.
  in Pathol Biol (Paris) (2003) Vol.51 pp64-6
  
• Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors
  Hanahan, D. Lanzavecchia, A. Mihich, E.
  in Cancer Res (2003) Vol.63 pp3005-8
  
• Antigen dependent and independent mechanisms that sustain serum antibody levels
  Traggiai, E. Puzone, R. Lanzavecchia, A.
  in Vaccine (2003) Vol.21 Suppl 2 ppS35-7
  
• Kinetics and expression patterns of chemokine receptors in human CD4+ T lymphocytes primed by myeloid or plasmacytoid dendritic cells
  Langenkamp, A. Nagata, K. Murphy, K. Lanzavecchia, A. Sallusto, F.
  in Eur J Immunol (2003) Vol.33 pp474-82
  
• T cell fitness determined by signal strength
  Gett, A. V. Sallusto, F. Lanzavecchia, A.
  in Nat Immunol (2003) Vol.4 pp355-60
  Antonio Lanzavecchia and Jens Geginat are co-corresponding authors.
• Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
  Geginat, J. Lanzavecchia, A. Sallusto, F.
  in Blood (2003) Vol.101 pp4260-6
  
• A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
  Bernasconi, N. L. Onai, N. Lanzavecchia, A.
  in Blood (2003) Vol.101 pp4500-4
  
• Maintenance of serological memory by polyclonal activation of human memory B cells
  Bernasconi, N. L. Traggiai, E. Lanzavecchia, A.
  in Science (2002) Vol.298 pp2199-202
  Nadia Bernasconi and Elisabetta Traggai contributed equally to this work.
• A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding
  Rachmilewitz, J. Lanzavecchia, A.
  in Trends Immunol (2002) Vol.23 pp592-5
  
• Progressive differentiation and selection of the fittest in the immune response
  Lanzavecchia, A. Sallusto, F.
  in Nat Rev Immunol (2002) Vol.2 pp982-7
  
• Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes
  Messi, M. Giacchetto, I. Nagata, K. Natoli, G. Sallusto, F.
  in Nat Immunol (2002) Vol.4 pp78-86
  
• TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines
  Geginat, J. Campagnaro, S. Sallusto, F.
  in Adv Exp Med Biol (2002) Vol.512 pp107-12
  
• Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells
  Bortoletto, N. Scotet, E. Myamoto, Y. Lanzavecchia, A.
  in Eur J Immunol (2002) Vol.32 pp3102-7
  
• T cell priming by dendritic cells: thresholds for proliferation, differentiation and death and intraclonal functional diversification
  Langenkamp, A. Casorati, G. Garavaglia, C. Lanzavecchia, A. Sallusto, F.
  in Eur J Immunol (2002) Vol.32 pp2046-54
  
• The instructive role of dendritic cells on T-cell responses
  Sallusto, F. Lanzavecchia, A.
  in Arthritis Res (2002) Vol.4 Suppl 3 ppS127-32
  
• Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes
  Yoneyama, H. Narumi, S. Zhang, Y. Baggiolini, M. Lanzavecchia, A. Ichida, T. Asakura, H. Matsushima, K.
  in J Exp Med (2002) Vol.195 pp1257-66
  
• The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells
  Engering, A. Geijtenbeek, T. B. van Vliet, S. J. van Liempt, E. Demaurex, N. Lanzavecchia, A. Fransen, J. Figdor, C. G. Piguet, V. van Kooyk, Y.
  in J Immunol (2002) Vol.168 pp2118-26
  
• Lack of fair play in the T cell response
  Lanzavecchia, A.
  in Nat Immunol (2001) Vol.3 pp9-10
  
• BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction
  Dzionek, A. Sohma, Y. Nagafune, J. Colonna, M. Facchetti, F. Gunther, G. Johnston, I. Lanzavecchia, A. Nagasaka, T. Okada, T. Vermi, W. Winkels, G. Yamamoto, T. Zysk, M. Yamaguchi, Y. Schmitz, J.
  in J Exp Med (2001) Vol.194 pp1823-34
  A. Dzionek, Y. Sohma, and J. Nagafune contributed equally to this work. Y. Yamaguchi and J. Schmitz share senior authorship for this work.
• Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells
  Geginat, J. Sallusto, F. Lanzavecchia, A.
  in J Exp Med (2001) Vol.194 pp1711-9
  
• Mouse pre-immunocytes as non-proliferating multipotent precursors of macrophages, interferon-producing cells, CD8alpha(+) and CD8alpha(-) dendritic cells
  Bruno, L. Seidl, T. Lanzavecchia, A.
  in Eur J Immunol (2001) Vol.31 pp3403-12
  
• Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
  Jarrossay, D. Napolitani, G. Colonna, M. Lanzavecchia, A.
  in Eur J Immunol (2001) Vol.31 pp3388-93
  
• Molecular regulation of CC-chemokine receptor 3 expression in human T helper 2 cells
  Scotet, E. Schroeder, S. Lanzavecchia, A.
  in Blood (2001) Vol.98 pp2568-70
  
• Exploring pathways for memory T cell generation
  Sallusto, F. Lanzavecchia, A.
  in J Clin Invest (2001) Vol.108 pp805-6
  
• Regulation of T cell immunity by dendritic cells
  Lanzavecchia, A. Sallusto, F.
  in Cell (2001) Vol.106 pp263-6
  Antonio Lanzavecchia and Federica Sallusto are co-corresponding authors.
• The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics
  Lanzavecchia, A. Sallusto, F.
  in Curr Opin Immunol (2001) Vol.13 pp291-8
  
• Antigen decoding by T lymphocytes: from synapses to fate determination
  Lanzavecchia, A. Sallusto, F.
  in Nat Immunol (2001) Vol.2 pp487-92
  
• Migration and function of antigen-primed nonpolarized T lymphocytes in vivo
  Iezzi, G. Scheidegger, D. Lanzavecchia, A.
  in J Exp Med (2001) Vol.193 pp987-93
  
• Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells
  Langenkamp, A. Messi, M. Lanzavecchia, A.
  in Nat Immunol (2001) Vol.1 pp311-6
  
• Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization
  Cella, M. Facchetti, F. Lanzavecchia, A.
  in Nat Immunol (2001) Vol.1 pp305-10
  
• Three signals and a master switch in the regulation of T-cell immunity
  Lanzavecchia, A.
  in Cold Spring Harb Symp Quant Biol (2001) Vol.64 pp253-7
  
• Organization of plasma membrane functional rafts upon T cell activation
  Tuosto, L. Parolini, I. Schroder, S. Lanzavecchia, A. Viola, A.
  in Eur J Immunol (2001) Vol.31 pp345-9
  
• Antigen processing and recognition
  Cresswell, P. Lanzavecchia, A.
  in Curr Opin Immunol (2001) Vol.13 pp11-2
  
• Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression
  Sallusto, F. Lanzavecchia, A.
  in Immunol Rev (2001) Vol.177 pp134-40
  
• A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response
  Dunbar, P. R. Smith, C. L. Chao, D. Shepherd, D. Mirza, F. Lipp, M. Lanzavecchia, A. Sallusto, F. Evans, A. Russell-Jones, R. Harris, A. L. Cerundolo, V.
  in J Immunol (2000) Vol.165 pp6644-52
  
• Functional subsets of memory T cells identified by CCR7 expression
  Sallusto, F. Langenkamp, A. Geginat, J.
  in Curr Top Microbiol Immunol (2000) Vol.251 pp167-71
  
• Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells
  Lanzavecchia, A. Sallusto, F.
  in Science (2000) Vol.290 pp92-7
  
• Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming
  Gagliardi, M. C. Sallusto, F. Marinaro, M. Lanzavecchia, A. De Magistris, M. T.
  in Eur J Immunol (2000) Vol.30 pp2394-403
  
• Dendritic cell maturation and generation of immune responses
  Lanzavecchia, A.
  in Haematologica (2000) Vol.84 Suppl EHA-4 pp23-5
  
• The role of chemokine receptors in primary, effector, and memory immune responses
  Sallusto, F. Mackay, C. R. Lanzavecchia, A.
  in Annu Rev Immunol (2000) Vol.18 pp593-620
  
• Cutting edge: recombinase-activating gene expression and V(D)J recombination in CD4+CD3low mature T lymphocytes
  Lantelme, E. Palermo, B. Granziero, L. Campanelli, R. Monafo, V. Lanzavecchia, A. Giachino, C.
  in J Immunol (2000) Vol.164 pp3455-9
  
• The role of aquaporins in dendritic cell macropinocytosis
  de Baey, A. Lanzavecchia, A.
  in J Exp Med (2000) Vol.191 pp743-8
  
• From synapses to immunological memory: the role of sustained T cell stimulation
  Lanzavecchia, A. Sallusto, F.
  in Curr Opin Immunol (2000) Vol.12 pp92-8
  
• Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells
  Salio, M. Cerundolo, V. Lanzavecchia, A.
  in Eur J Immunol (2000) Vol.30 pp705-8
  
• Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation
  Macagno, A. Gilliet, M. Sallusto, F. Nestle, F. O. Groettrup, M.
  in Eur J Immunol (1999) Vol.29 pp4037-42
  
• The interplay between the duration of TCR and cytokine signaling determines T cell polarization
  Iezzi, G. Scotet, E. Scheidegger, D.
  in Eur J Immunol (1999) Vol.29 pp4092-101
  
• Inhibition of dendritic cell maturation by herpes simplex virus
  Salio, M. Cella, M. Suter, M.
  in Eur J Immunol (1999) Vol.29 pp3245-53
  
• Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
  Sallusto, F. Lenig, D. Forster, R. Lanzavecchia, A.
  in Nature (1999) Vol.401 pp708-12
  
• T-cell activation and the dynamic world of rafts
  Viola, A. Lanzavecchia, A.
  in APMIS (1999) Vol.107 pp615-23
  
• Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
  Cella, M. Jarrossay, D. Facchetti, F. Nakajima, H. Lanzavecchia, A. Colonna, M.
  in Nat Med (1999) Vol.5 pp919-23
  
• The role of chemokine receptors in directing traffic of naive, type 1 and type 2 T cells
  Sallusto, F. Palermo, B. Hoy, A.
  in Curr Top Microbiol Immunol (1999) Vol.246 pp123-8; discussion 129
  
• Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
  Sallusto, F. Kremmer, E. Palermo, B. Ponath, P. Qin, S. Forster, R. Lipp, M. Lanzavecchia, A.
  in Eur J Immunol (1999) Vol.29 pp2037-45
  
• Distinct patterns and kinetics of chemokine production regulate dendritic cell function
  Sallusto, F. Palermo, B. Lenig, D. Matikainen, S. Julkunen, I. Forster, R. Burgstahler, R. Lipp, M. Lanzavecchia, A.
  in Eur J Immunol (1999) Vol.29 pp1617-25
  
• Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells
  Bachmann, M. F. Gallimore, A. Linkert, S. Lanzavecchia, A. Kopf, M. Viola, A.
  in J Exp Med (1999) Vol.189 pp1521-30
  
• Maturation, activation, and protection of dendritic cells induced by double-stranded RNA
  Cella, M. Salio, M. Sakakibara, Y. Julkunen, I. Lanzavecchia, A.
  in J Exp Med (1999) Vol.189 pp821-9
  
• Mobilizing dendritic cells for tolerance, priming, and chronic inflammation
  Sallusto, F. Lanzavecchia, A.
  in J Exp Med (1999) Vol.189 pp611-4
  
• From TCR engagement to T cell activation: a kinetic view of T cell behavior
  Lanzavecchia, A. Lezzi, G. Viola, A.
  in Cell (1999) Vol.96 pp1-4
  
• Peptide binding and editing: generation of TCR ligands
  Hammerling, G. J. Manoury, B. Watts, C. Lanzavecchia, A.
  in Res Immunol (1999) Vol.149 pp863-5
  
• T lymphocyte costimulation mediated by reorganization of membrane microdomains
  Viola, A. Schroeder, S. Sakakibara, Y.
  in Science (1999) Vol.283 pp680-2
  
• Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
  Sallusto, F. Lanzavecchia, A. Mackay, C. R.
  in Immunol Today (1998) Vol.19 pp568-74
  
• From antigen presentation to T-cell activation
  Lanzavecchia, A.
  in Res Immunol (1998) Vol.149 pp626
  
• Re-expression of RAG-1 and RAG-2 genes and evidence for secondary rearrangements in human germinal center B lymphocytes
  Giachino, C. Padovan, E. Lanzavecchia, A.
  in Eur J Immunol (1998) Vol.28 pp3506-13
  
• Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
  Sallusto, F. Schaerli, P. Loetscher, P. Lenig, D. Mackay, C. R. Qin, S. Lanzavecchia, A.
  in Eur J Immunol (1998) Vol.28 pp2760-9
  
• Immunology. Licence to kill
  Lanzavecchia, A.
  in Nature (1998) Vol.393 pp413-4
  
• Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
  Sallusto, F. Lenig, D. Mackay, C. R.
  in J Exp Med (1998) Vol.187 pp875-83
  
• The duration of antigenic stimulation determines the fate of naive and effector T cells
  Iezzi, G. Karjalainen, K. Lanzavecchia, A.
  in Immunity (1998) Vol.8 pp89-95
  
• Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA
  Molinari, M. Salio, M. Galli, C. Rappuoli, R. Lanzavecchia, A. Montecucco, C.
  in J Exp Med (1998) Vol.187 pp135-40
  
• Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
  Viola, A. Salio, M. Tuosto, L. Acuto, O. Lanzavecchia, A.
  in J Exp Med (1997) Vol.186 pp1775-9
  
• A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies
  Viola, A. Linkert, S. Lanzavecchia, A.
  in Eur J Immunol (1997) Vol.27 pp3080-3
  
• The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells
  Engering, A. J. Cella, M. Fluitsma, D. Hoefsmit, E. C. Lanzavecchia, A. Pieters, J.
  in Eur J Immunol (1997) Vol.27 pp2417-25
  
• Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells
  Sallusto, F. Mackay, C. R. Lanzavecchia, A.
  in Science (1997) Vol.277 pp2005-7
  
• Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
  Cella, M. Engering, A. Pinet, V. Lanzavecchia, A.
  in Nature (1997) Vol.388 pp782-7
  
• CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor alpha: II. Functional analysis
  Caux, C. Massacrier, C. Vanbervliet, B. Durand, I. Cella, M. Lanzavecchia, A. Banchereau, J.
  in Blood (1997) Vol.90 pp1458-70
  
• Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation
  Salio, M. Valitutti, S. Lanzavecchia, A.
  in Eur J Immunol (1997) Vol.27 pp1769-73
  
• Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition
  Valitutti, S. Lanzavecchia, A.
  in Immunol Today (1997) Vol.18 pp299-304
  
• A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing
  Cella, M. Dohring, C. Samaridis, J. Brockhaus, M. Lanzavecchia, A. Colonna, M.
  in J Exp Med (1997) Vol.185 pp1743-51
  
• Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation
  Valitutti, S. Muller, S. Salio, M.
  in J Exp Med (1997) Vol.185 pp1859-64
  
• Understanding the mechanisms of sustained signaling and T cell activation
  Lanzavecchia, A.
  in J Exp Med (1997) Vol.185 pp1717-9
  
• Baculovirus cDNA libraries for expression cloning of genes encoding cell-surface antigens
  Granziero, L. Nelboeck, P. Bedoucha, M. Reid, H. H.
  in J Immunol Methods (1997) Vol.203 pp131-9
  
• Origin, maturation and antigen presenting function of dendritic cells
  Cella, M. Sallusto, F. Lanzavecchia, A.
  in Curr Opin Immunol (1997) Vol.9 pp10-6
  
• Mannose receptor mediated antigen uptake and presentation in human dendritic cells
  Engering, A. J. Cella, M. Fluitsma, D. M. Lanzavecchia, A. Pieters, J.
  in Adv Exp Med Biol (1997) Vol.417 pp183-7
  
• Restricted TCR repertoire and long-term persistence of donor-derived antigen-experienced CD4+ T cells in allogeneic bone marrow transplantation recipients
  Vavassori, M. Maccario, R. Moretta, A. Wack, A. Locatelli, F. Lanzavecchia, A. Maserati, E. Dellabona, P. Casorati, G. Montagna, D.
  in J Immunol (1996) Vol.157 pp5739-47
  
• Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates
  Valitutti, S. Muller, S. Dessing, M.
  in Eur J Immunol (1996) Vol.26 pp2012-6
  
• Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
  Cella, M. Scheidegger, D. Palmer-Lehmann, K. Lanzavecchia, A. Alber, G.
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• Mechanisms of antigen uptake for presentation
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• Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
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• Presentation of peptides by cultured monocytes or activated T cells allows specific priming of human cytotoxic T lymphocytes in vitro
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• Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines
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• Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products
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• Dual receptor T-cells. Implications for alloreactivity and autoimmunity
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• CD40 ligand-independent B cell activation revealed by CD40 ligand-deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation
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• How can cryptic epitopes trigger autoimmunity?
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• Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
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• Serial triggering of many T-cell receptors by a few peptide-MHC complexes
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• Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion
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• kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire
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• Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
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• T cell epitope analysis with peptides simultaneously synthesized on cellulose membranes: fine mapping of two DQ dependent epitopes
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• Peptide partners call the tune
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• An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells
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• Clonal expansions of V delta 1+ and V delta 2+ cells increase with age and limit the repertoire of human gamma delta T cells
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• T-helper- and accessory-cell-independent cytotoxic responses to human tumor cells transfected with a B7 retroviral vector
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• Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
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  * “Pillars of Immunology” section of The Journal of Immunology features this article in February 1, 2018: http://www.jimmunol.org/content/200/3/885 http://www.jimmunol.org/ImmunoCasts
• Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles
  Valmori, D. Sabbatini, A. Lanzavecchia, A. Matricardi, P. M.
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• Professional presentation of antigen by activated human T cells
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• Expression of two T cell receptor alpha chains: dual receptor T cells
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• Suppressive effect of antibody on processing of T cell epitopes
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• Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1
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• In vivo persistence of expanded clones specific for bacterial antigens within the human T cell receptor alpha/beta CD4-8- subset
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• Identifying strategies for immune intervention
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• Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility
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• Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation
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• The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86
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• Presentation of self-peptides: consequences for self nonself discrimination and allorecognition
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• Identification of HLA-DR alpha chain residues critical for binding of the toxic shock syndrome toxin superantigen
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• Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes
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• T cell clones with normal or defective O-galactosylation from a patient with permanent mixed-field polyagglutinability
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• Irreversible association of peptides with class II MHC molecules in living cells
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• Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition
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• Adoptive immunotherapy of ovarian carcinoma with bs-MAb-targeted lymphocytes: a multicenter study
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• Janusin: new molecular design for bispecific reagents
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• Bispecific single chain molecules (Janusins) target cytotoxic lymphocytes on HIV infected cells
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• Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes
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• Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions
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• Recognition by class II alloreactive T cells of processed determinants from human serum proteins
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• Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells
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• Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells
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• Chemical and functional analysis of MHC class II-restricted T cell epitopes
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• Correlation between TCR V gene usage and antigen specificities in human gamma delta T cells
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• New perspectives on immunointervention in autoimmune diseases
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• T cell activation by a bispecific anti-CD3/anti-major histocompatibility complex class I antibody
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• Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
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• Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways
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• Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells
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• Molecular analysis of human gamma/delta+ clones from thymus and peripheral blood
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• A novel and simple procedure for determining T cell epitopes in protein antigens
  Demotz, S. Matricardi, P. Lanzavecchia, A.
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• Establishment of human double-positive thymocyte clones
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• Triggering T cells by otherwise inert hybrid anti-CD3/antitumor antibodies requires encounter with the specific target cell
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• How many ways can a killer cell kill?
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• Is suppression a function of class II–restricted cytotoxic T cells?
  Lanzavecchia, A.
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• In vivo localization of a bispecific antibody which targets human T lymphocytes to lyse human colon cancer cells
  Barr, I. G. Miescher, S. von Fliedner, V. Barras, C. Lanzavecchia, A. Mach, J. P. Carrel, S.
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• Delineation of several DR-restricted tetanus toxin T cell epitopes
  Demotz, S. Lanzavecchia, A. Eisel, U. Widmann, C. Corradin, G.
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• Harming and protecting responses to HIV
  Lanzavecchia, A.
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• Study on the immunogenicity of human class-II-restricted T-cell epitopes: processing constraints, degenerate binding, and promiscuous recognition
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• Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes
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• Clonal sketches of the immune response
  Lanzavecchia, A.
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• Activation of mononuclear cells to be used for hybrid monoclonal antibody-induced lysis of human ovarian carcinoma cells
  Pupa, S. M. Canevari, S. Fontanelli, R. Mezzanzanica, D. Lanzavecchia, A. Colnaghi, M. I.
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• T cells can present antigens such as HIV gp120 targeted to their own surface molecules
  Lanzavecchia, A. Roosnek, E. Gregory, T. Abrignani, S.
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• Kinetics of MHC-antigen complex formation on antigen-presenting cells
  Roosnek, E. Demotz, S. Corradin, G.
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• Exploiting the immune system’s own strategies for immunotherapy
  Lanzavecchia, A.
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• Human ovarian carcinoma lysis by cytotoxic T cells targeted by bispecific monoclonal antibodies: analysis of the antibody components
  Mezzanzanica, D. Canevari, S. Menard, S. Tagliabue, E. Lanzavecchia, A. Colnaghi, M. I.
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• Antibodies as antigens. The use of mouse monoclonal antibodies to focus human T cells against selected targets
  Lanzavecchia, A. Abrignani, S. Scheidegger, D. Dorken, B. Moldenhauer, G.
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• Anti-ovarian carcinoma anti-T3 heteroconjugates or hybrid antibodies induce tumor cell lysis by cytotoxic T-cells
  Canevari, S. Menard, S. Mezzanzanica, D. Pupa, S. M. Lanzavecchia, A. Colnaghi, M. I.
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• Antigen uptake and accumulation in antigen-specific B cells
  Lanzavecchia, A.
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• Lysis of nonnucleated red blood cells by cytotoxic T lymphocytes
  Lanzavecchia, A. Staerz, U. D.
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• The use of hybrid hybridomas to target human cytotoxic T lymphocytes
  Lanzavecchia, A. Scheidegger, D.
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• Advances in understanding of mechanisms of IgE disregulation in atopy by the application of in vitro methods
  Ricci, M. Del Prete, G. F. Maggi, E. Romagnani, S.
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• Is the T-cell receptor involved in T-cell killing?
  Lanzavecchia, A.
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• Antigen presentation by B lymphocytes: a critical step in T-B collaboration
  Lanzavecchia, A.
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• Isolation and characterization of Ni-specific T cell clones from patients with Ni-contact dermatitis
  Sinigaglia, F. Scheidegger, D. Garotta, G. Pletscher, M. Lanzavecchia, A.
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• Specific B lymphocytes efficiently pick up, process and present antigen to T cells
  Lanzavecchia, A. Bove, S.
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• Antigen-specific interaction between T and B cells
  Lanzavecchia, A.
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• A dramatic representation of immunological cooperative events
  Celada, F. Lanzavecchia, A.
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• In vitro synthesis of human IgE: reappraisal of a 5-year study
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• In vitro stimulation of IgE production at a single precursor level by human alloreactive T helper clones
  Lanzavecchia, A. Parodi, B.
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• The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
  Ramarli, D. Parodi, B. Fabbi, M. Lanzavecchia, A.
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• One out of five peripheral blood B lymphocytes is activated to high-rate Ig production by human alloreactive T cell clones
  Lanzavecchia, A.
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• Activation of human B lymphocytes: frequency of antigen-specific B cells triggered by alloreactive or by antigen-specific T cell clones
  Lanzavecchia, A. Parodi, B. Celada, F.
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• In vitro selective expansion of allergen specific T cells from atopic patients
  Lanzavecchia, A. Santini, P. Maggi, E. Falagiani, P. Romagnani, S. Ferrarini, M.
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• Human T cell lines with antigen specificity and helper activity
  Lanzavecchia, A. Ferrarini, M. Celada, F.
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• Ontogeny of secretory immunity: levels of secretory IgA and natural antibodies in saliva
  Burgio, G. R. Lanzavecchia, A. Plebani, A. Ugazio, A. G.
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• Activation of human peripheral blood lymphocytes: effect of concanavalin A and lipopolysaccharide on in vitro synthesis of DNA and immunoglobulins
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• Concanavalin A induces a T-cell dependent activation of human tonsil B cells in vitro
  Vitiello, A. Nespoli, L. Lanzavecchia, A. Ugazio, A. G.
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• Effect of in vitro treatment with reducing drugs on structure and function of human secretory immunoglobulin A
  Plebani, A. Lanzavecchia, A. Forsgren, U. Ugazio, A. G. Ortengren, B. Burgio, G. R.
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• Plaque assay with protein A-coated erythrocytes for the evaluation of human immunoglobulin-secreting cells induced by pokeweed mitogen
  Lanzavecchia, A. Sacchi, G. Maccario, R. Nespoli, L. Ugazio, A. G.
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• Immunodeficiency in Down’s syndrome. Titres of “natural” antibodies to E. coli and rabbit erythrocytes at different ages
  Ugazio, A. G. Lanzavecchia, A. Jayakar, S. Duse, M. Burgio, G. R.
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• Immunodeficiency in Down’s syndrome: T-lymphocyte subset imbalance in trisomic children
  Burgio, G. R. Lanzavecchia, A. Maccario, R. Plebani, A. Ugazio, A. G.
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• Common variable immunodeficiency: long term clinical consequencies of splenectomy in a case of late-onset hypogammaglobulinaemia
  Lanzavecchia, A. Frassoni, F. Piovella, F. Maccario, R. Ugazio, A. G.
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• Polyclonal activation of human B lymphocytes in vitro by pokeweed mitogen: a simple technique for the simultaneous assessment of cell proliferation, generation of plasma cells, plaque-forming cells and immunoglobulin production
  Nespoli, L. Vitiello, A. Maccario, R. Ugazio, A. G.
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• Human T lymphocyte subset identification according to avidity for sheep erythrocytes and rosetting capacity with allogeneic red blood cells
  Lanzavecchia, A. Maccario, R. Vitiello, A. Ugazio, A. G.
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