Perez Laurent, PhD

Publications -> 20816

• AncesTree: An interactive immunoglobulin lineage tree visualizer
  Foglierini, M. Pappas, L. Lanzavecchia, A. Corti, D. Perez, L.
  in PLoS Comput Biol (2020) Vol.16 ppe1007731
  
• A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients
  Cassotta, A. Mikol, V. Bertrand, T. Le Parc, J. Ferrari, P. Dumas, J. Auer, M. Deisenhammer, F. Gastaldi, M. Franciotta, D. Silacci-Fregni, C. Fernandez Rodriguez, B. Giacchetto-Sasselli, I. Foglierini, M. Jarrossay, D. Geiger, R. Sallusto, F. Lanzavecchia, A. Piccoli, L.
  in Nat Med (2019) Vol.25 pp1402-1407
  
• HCMV Envelope Glycoprotein Diversity Demystified
  Foglierini, M. Marcandalli, J. Perez, L.
  in Front Microbiol (2019) Vol.10 pp1005
  
• T cells in patients with narcolepsy target self-antigens of hypocretin neurons
  Latorre, D. Kallweit, U. Armentani, E. Mele, F. Cassotta, A. Jovic, S. Jarrossay, D. Mathis, J. Zellini, F. Becher, B. Lanzavecchia, A. Khatami, R. Manconi, M. Tafti, M. Bassetti, C. L. Sallusto, F.
  in Nature (2018) Vol.562 pp63-68
  
• An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells
  Aschenbrenner, D. Foglierini, M. Jarrossay, D. Weiner, H. L. Kuchroo, V. K. Lanzavecchia, A. Notarbartolo, S. Sallusto, F.
  in Nat Immunol (2018) Vol.19 pp1126-1136
  
• An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor
  Martinez-Martin, N. Marcandalli, J. Huang, C. S. Perotti, M. Foglierini, M. Ho, H. Dosey, A. M. Shriver, S. Payandeh, J. Leitner, A. Lanzavecchia, A. Perez, L. Ciferri, C.
  in Cell (2018) Vol.174 pp1158-1171
  * L. Perez and C. Ciferri contributed equally; N M-M, LP and CC are co-corresponding authors
• A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
  Tan, J. Sack, B. K. Oyen, D. Piccoli, L. Barbieri, S. Foglierini, M. Fregni, C. S. Marcandalli, J. Jongo, S. Abdulla, S. Perez, L. Corradin, G. Varani, L. Sallusto, F. Sim, B. K. L. Hoffman, S. L. Kappe, S. H. I. Daubenberger, C. Wilson, I. A. Lanzavecchia, A.
  in Nat Med (2018) Vol.24 pp401-407
  * Tan J., Sack B. K., Oyen D., Zenklusen I., Piccoli L. contributed equally to this work.
• A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
  Wang, J. Bardelli, M. Espinosa, D. A. Ng, T. S. Bianchi, S. Simonelli, L. Lim, E. X. Y. Foglierini, M. Zatta, F. Jaconi, S. Beltramello, M. Cameroni, E. Fibriansah, G. Shi, J. Barca, T. Pagani, I. Rubio, A. Broccoli, V. Vicenzi, E. Graham, V. Pullan, S. Dowall, S. Hewson, R. Jurt, S.Zerbe, O. Stettler, K. Lanzavecchia, A. Sallusto, F. Cavalli, A.
  in Cell (2017) Vol.171 pp229-241 e15
  * J. Wang and M. Bardelli contributed equally ; S-M Lok, L.Varani and D. Corti contributed equally.
• Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
  Pieper, K. Tan, J. Piccoli, L. Barbieri, S. Chen, Y. Silacci-Fregni, C. Wolf, T. Jarrossay, D. Anderle, M. Abdi, A. Ndungu, F. M. Doumbo, O. K. Traore, B. Tran, T. M. Jongo, S. Zenklusen, I. Crompton, P. D. Daubenberger, C. Bull, P. C. Sallusto, F. Lanzavecchia, A.
  in Nature (2017) Vol.548 pp597-601
  * Pieper K., Tan J., Piccoli, L. contributed equally to this work.
• Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? T-Cell Heterogeneity, Plasticity, and Selection in Humans
  Sallusto, F. Cassotta, A. Hoces, D. Lanzavecchia, A.
  in Cold Spring Harb Perspect Biol (2017) Vol.10 ppa029421
  
• Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes
  Kallewaard, N. L. Corti, D. Collins, P. J. McAuliffe, J. M. Benjamin, E. Wachter-Rosati, L. Palmer-Hill, F. J. Yuan, A. Q. Walker, P. A. Vorlaender, M. K. Bianchi, S. Guarino, B. De Marco, A. Vanzetta, F. Agatic, G. Foglierini, M. Pinna, D. Fernandez-Rodriguez, B. Fruehwirth, A. Silacci, C. Ogrodowicz, R. W. Martin, S. R. Sallusto, F. Suzich, J. A. Lanzavecchia, A. Zhu, Q. Gamblin, S. J. Skehel, J. J.
  in Cell (2016) Vol.166 pp596-608
  
• Platelet-derived growth factor-alpha receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer
  Kabanova, A. Marcandalli, J. Zhou, T. Baxa, U. Tsybovsky, Y. Lilleri, D. Silacci-Fregni, C. Foglierini, M. Fernandez-Rodriguez, B. M. Druz, A. Zhang, B. Geiger, R. Pagani, M. Sallusto, F. Kwong, P. D. Corti, D. Lanzavecchia, A. Perez, L.
  in Nat Microbiol (2016) Vol.1 pp16082
  Anna Kabanova, Jessica Marcandalli, Tongqing Zhou equally contributed to this work; Antonio Lanzavecchia1and Laurent Perez jointly supervised this work.
• Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis
  De Benedictis, P. Minola, A. Rota Nodari, E. Zecchin, B. Salomoni, A. Foglierini, M. Agatic, G. Vanzetta, F. Lavenir, R. Lepelletier, A. Bentley, E. Weiss, R. Cattoli, G. Capua, I. Sallusto, F. Wright, E. Lanzavecchia, A. Bourhy, H. Corti, D.
  in EMBO Mol Med (2016) Vol.8 pp407-21
  Paola De Benedictis and Andrea Minola equally contributed to this work.
• A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens
  Tan, J. Pieper, K. Piccoli, L. Foglierini, M. Geiger, R. Tully, C. M. Jarrossay, D. Ndungu, F. M. Wambua, J. Bejon, P. Fregni, C. S. Fernandez-Rodriguez, B. Barbieri, S. Bianchi, S. Marsh, K. Thathy, V. Corti, D. Sallusto, F. Bull, P. Lanzavecchia, A.
  in Nature (2016) Vol.529 pp105-9
  Joshua Tan, Kathrin Pieper, Luca Piccoli equally contributed to this work and Peter Bull and Antonio Lanzavecchia jointly supervised this work.
• Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells
  Preite, S. Baumjohann, D. Foglierini, M. Ronchi, F. Rodriguez, B. M. Corti, D. Lanzavecchia, A. Sallusto, F.
  in Eur J Immunol (2015) Vol.45 pp3010-21
  
• Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
  Corti, D. Zhao, J. Pedotti, M. Agnihothram, S. Fett, C. Fernandez-Rodriguez, B. Foglierini, M. Agatic, G. Vanzetta, F. Gopal, R. Langrish, C. J. Barrett, N. A. Sallusto, F. Baric, R. S. Varani, L. Zambon, M. Perlman, S. Lanzavecchia, A.
  in Proc Natl Acad Sci U S A (2015) Vol.112 pp10473-8
  D.C. and J.Z. contributed equally to this work.
• Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody
  Xiong, X. Corti, D. Liu, J. Foglierini, M. Calder, L. J. Martin, S. R. Lin, Y. P. Walker, P. A. Collins, P. J. Monne, I. Suguitan, A. L., Jr. Santos, C. Temperton, N. J. Subbarao, K. Lanzavecchia, A. Gamblin, S. J. Skehel, J. J.
  in Proc Natl Acad Sci U S A (2015) Vol.112 pp9430-5
  X.X., D.C., and J.L. contributed equally to this work.
• T cell immunity. Functional heterogeneity of human memory CD4(+) T cell clones primed by pathogens or vaccines
  Becattini, S. Latorre, D. Mele, F. De Gregorio, C. Cassotta, A. Fernandez, B. Kelderman, S. Schumacher, T. N. Corti, D. Lanzavecchia, A. Sallusto, F.
  in Science (2014) Vol.347 pp400-6
  Abstract Reprint Full Text
• Rapid development of broadly influenza neutralizing antibodies through redundant mutations
  Pappas, L. Foglierini, M. Piccoli, L. Turrini, F. Silacci, C. Fernandez-Rodriguez, B. Agatic, G. Giacchetto-Sasselli, I. Pellicciotta, G. Sallusto, F. Zhu, Q. Vicenzi, E. Corti, D. Lanzavecchia, A.
  in Nature (2014) Vol.516 pp418-22
  Davide Corti and Antonio Lanzavecchia equally contributed to this work.