Fasana Elisa, PhD

Protein Folding and Quality Control
Research Assistant

Via Vela, 6
6500 Bellinzona, Switzerland

Bio

Elisa Fasana achieved her Master degree in Medical Biotechnology and Molecular Medicine in 2007 at the Institute of Neuroscience of the National Research Council (Milan, Italy). During her research project she characterized the intracellular localization of a mutant form of the vesicle-trafficking protein VAPB, P56S-VAPB, which was reported to be linked to an autosomal form of amyotrophic lateral sclerosis (ALS). She obtained her PhD degree in 2011. During her PhD thesis she investigated the transmembrane-dependent partitioning into the endoplasmic reticulum (ER) focalizing on the resident ER protein cytochrome b5. She joined the group of Maurizio Molinari at the IRB in October 2011.

Publications -> 18611

Endoplasmic Reticulum and Lysosomal Quality Control of Four Nonsense Mutants of Iduronate 2-Sulfatase Linked to Hunter’s Syndrome
Marazza, A. Galli, C. Fasana, E. Burda, P. Fassi, E. M. A. Baumgartner, M. Cavalli, A. Molinari, M.
in DNA Cell Biol (2020) Vol.39 pp226-234
A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex
Forrester, A. De Leonibus, C. Grumati, P. Piemontese, M. Staiano, L. Fregno, I. Raimondi, A. Marazza, A. Bruno, G. Iavazzo, M. Intartaglia, D. Seczynska, M. van Anken, E. Conte, I. De Matteis, M. A. Dikic, I. Molinari, M. Settembre, C.
in EMBO J (2018) Vol.38 ppe99847
ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport
Fregno, I. Fasana, E. Bergmann, T. J. Loi, M. Solda, T. Galli, C. D'Antuono, R. Morone, D. Danieli, A. Paganetti, P. van Anken, E. Molinari, M.
in EMBO J (2018) Vol.37 ppe99259
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
Fumagalli, F. Noack, J. Bergmann, T. J. Pisoni, G. B. Fasana, E. Fregno, I. Galli, C. Loi, M. Solda, T. D'Antuono, R. Raimondi, A. Jung, M. Melnyk, A. Schorr, S. Schreiber, A. Simonelli, L. Varani, L. Wilson-Zbinden, C. Zerbe, O. Hofmann, K. Peter, M. Quadroni, M. Zimmermann, R. Molinari, M.
in Nat Cell Biol (2016) Vol.18 pp1173-1184
Fumagalli, F. , Noack J. and Bergmann T. contributed equally to this work. * Recommended by the Faculty of 1000
Specificity and regulation of the endoplasmic reticulum-associated degradation machinery
Merulla, J. Fasana, E. Solda, T.
in Traffic (2013) Vol.14 pp767-77

Fasana Elisa, PhD

Bio

Publications -> 18611

Institute for Research in Biomedicine

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