Mele Federico, PhD

Publications -> 18662

• Human IFN-gamma immunity to mycobacteria is governed by both IL-12 and IL-23
  Martinez-Barricarte, R. Markle, J. G. Ma, C. S. Ramirez-Alejo, N. Mele, F. Latorre, D. Mahdaviani, S. A. Aytekin, C. Mansouri, D. Bryant, V. L. Jabot-Hanin, F. Deswarte, C. Nieto-Patlan, A. Surace, L. Kerner, G. Itan, Y. Jovic, S. Avery, D. T. Wong, N. Rao, G. Patin, E. Okada, S. Bigio, B. Boisson, B. Rapaport, F. Seeleuthner, Y. Schmidt, M. Ikinciogullari, A. Dogu, F.
  in Sci Immunol (2018) Vol.3 ppii: eaau6759
  
• T cells in patients with narcolepsy target self-antigens of hypocretin neurons
  Latorre, D. Kallweit, U. Armentani, E. Mele, F. Cassotta, A. Jovic, S. Jarrossay, D. Mathis, J. Zellini, F. Becher, B. Lanzavecchia, A. Khatami, R. Manconi, M. Tafti, M. Bassetti, C. L. Sallusto, F.
  in Nature (2018) Vol.562 pp63-68
  
• Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
  Kong, X. F. Martinez-Barricarte, R. Kennedy, J. Lazarov, T. Deenick, E. K. Ma, C. S. Breton, G. Lucero, K. B. Langlais, D. Bousfiha, A. Aytekin, C. Markle, J. Trouillet, C. Jabot-Hanin, F. Arlehamn, C. S. L. Rao, G. Picard, C. Lasseau, T. Latorre, D. Hambleton, S. Deswarte, C. Itan, Y. Abarca, K. Moraes-Vasconcelos, D. Ailal, F. Ikinciogullari, A. Dogu, F. Benhsaien, I. Sette, A.
  in Nat Immunol (2018) Vol.19 pp973-985
  
• Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with protection from vertical transmission
  Mele, F. Fornara, C. Jarrossay, D. Arossa, A. Spinillo, A. Lanzavecchia, A. Gerna, G. Sallusto, F. Lilleri, D.
  in PLoS One (2017) Vol.12 ppe0187731
  
• Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection
  Stettler, K. Beltramello, M. Espinosa, D. A. Cassotta, A. Bianchi, S. Vanzetta, F. Minola, A. Jaconi, S. Mele, F. Foglierini, M. Pedotti, M. Simonelli, L. Dowall, S. Atkinson, B. Percivalle, E. Simmons, C. P. Varani, L. Blum, J. Baldanti, F. Cameroni, E. Hewson, R. Harris, E. Lanzavecchia, A. Sallusto, F. Corti, D.
  in Science (2016) Vol.353 pp823-6
  K. S and M. B contributed equally to this work; D. A. E. ; V. G. ; A. C. ; S. B. and F. V contributed equally to this work; F. S. and D. C contributed equally to this work and are co-corresponding authors.
• Follicular helper T-cells and virus-specific antibody response in primary and reactivated human cytomegalovirus infections of the immunocompetent and immunocompromised transplanted patients
  Bruno, F. Fornara, C. Zelini, P. Carrara, E. Scaramuzzi, L. Cane, I. Mele, F. Sallusto, F. Lilleri, D. Gerna, G.
  in J Gen Virol (2016) Vol.97 pp1928-41
  
• IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
  Okada, S. Markle, J. G. Deenick, E. K. Averbuch, D. Lagos, M. Alzahrani, M. Al-Muhsen, S. Halwani, R. Ma, C. S. Wong, N. Soudais, C. Henderson, L. A. Marzouqa, H. Shamma, J. Gonzalez, M. Martinez-Barricarte, R. Okada, C. Avery, D. T. Latorre, D. Deswarte, C. Jabot-Hanin, F. Torrado, E. Fountain, J. Belkadi, A. Itan, Y. Boisson, B. Migaud, M. Arlehamn, C. S. Sette, A.
  in Science (2015) Vol.349 pp606-13
  
• ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
  Mele, F. Basso, C. Leoni, C. Becattini, S. Latorre, D. Lanzavecchia, A. Sallusto, F. Monticelli, S.
  in Nat Commun (2015) Vol.6 pp6431
  Federica Sallusto and Silvia Monticelli equally contributed to this work and are co-corresponding authors.
• T cell immunity. Functional heterogeneity of human memory CD4(+) T cell clones primed by pathogens or vaccines
  Becattini, S. Latorre, D. Mele, F. De Gregorio, C. Cassotta, A. Fernandez, B. Kelderman, S. Schumacher, T. N. Corti, D. Lanzavecchia, A. Sallusto, F.
  in Science (2014) Vol.347 pp400-6
  Abstract Reprint Full Text
• Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes
  Lindestam Arlehamn, C. S. Paul, S. Mele, F. Greenbaum, J. A. Vita, R. Sidney, J. Peters, B. Sallusto, F. Sette, A.
  in Proc Natl Acad Sci U S A (2014) Vol.112 ppE147-55
  
• Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3(+)CCR6(+) Th1 Subset
  Lindestam Arlehamn, C. S. Gerasimova, A. Mele, F. Swann, J. Greenbaum, J. A. Kim, Y. Sidney, J. James, E. A. Taplitz, R. McKinney, D. M. Kwok, W. W. Grey, H. Sallusto, F. Peters, B. Sette, A.
  in PLoS Pathog (2013) Vol.9 ppe1003130
  
• Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta
  Zielinski, C. E. Mele, F. Aschenbrenner, D. Ronchi, F. Gattorno, M. Monticelli, S. Lanzavecchia, A. Sallusto, F.
  in Nature (2012) Vol.484 pp514-8
  
• Dissecting the human immunologic memory for pathogens
  Zielinski, C. E. Corti, D. Mele, F. Lanzavecchia, A. Sallusto, F.
  in Immunol Rev (2011) Vol.240 pp40-51